Email this article The first representatives of phosphonium salts based on the ammonium acylhydrazone scaffold: synthesis and biological activity
- Authors: Bogdanov A.V.1, Bukharov S.V.2, Rozhkova M.A.2, Voloshina A.D.3
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Affiliations:
- Kazan (Volga region) Federal University
- Kazan National Research Technological University
- A.E. Arbuzov Institute of Organic and Physical Chemistry, Federal Reseatch Center “Kazan Scientific Center of the Russian Academy of Sciences”
- Issue: Vol 93, No 12 (2023)
- Pages: 1912-1916
- Section: Articles
- URL: https://journals.rcsi.science/0044-460X/article/view/247229
- DOI: https://doi.org/10.31857/S0044460X23120107
- EDN: https://elibrary.ru/OCLRLA
- ID: 247229
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Abstract
The acid-catalyzed reaction of substituted benzaldehydes with Girard’s reagent T leads to the formation of new water-soluble mixed ammonium-phosphonium salts. The obtained compounds exhibit high antimicrobial and moderate antitumor activities with low hemotoxicity.
Keywords
About the authors
A. V. Bogdanov
Kazan (Volga region) Federal University
Email: abogdanov@inbox.ru
S. V. Bukharov
Kazan National Research Technological University
M. A. Rozhkova
Kazan National Research Technological University
A. D. Voloshina
A.E. Arbuzov Institute of Organic and Physical Chemistry, Federal Reseatch Center “Kazan Scientific Center of the Russian Academy of Sciences”
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