Modern trends of the incidence of syphilis in the areas of Ural Federal District

BACKGROUND: The incidence of syphilis is an indicator of social disadvantage in society as a whole and in particular regions, and is mostly determined by medical, social, biological and economic factors.

AIM: To study modern clinical and epidemiological aspects and assess epidemic trends of syphilis in the population of the Ural Federal District for the period from 2014 to 2022 in order to determine further preventive epidemic control measures.

MATERIALS AND METHODS: The object of the study are the data of statistical forms No. 9 and No. 34 on the number of registered cases of syphilis in the Ural Federal District for the period from 2014 to 2021, the data of statistical materials "Resources and activities of medical organizations of dermatovenerological profile. Incidence of sexually transmitted infections, contagious skin diseases and skin diseases" and operational data for 6 months of 2021 and 2022 years. Intensive and extensive morbidity rates are calculated and their analysis using descriptive statistics is presented.

RESULTS: The main patterns of the course of syphilitic infection in six subjects (which are parts of the Ural Federal District) of the Russian Federation have been studied. Modern clinical and epidemiological features and trends have been established: variability of morbidity indicators, its clinical structure and territorial dynamics; variability in the age-associated characteristics of patients, the emergence of high-risk groups have been noted. Target indicators characterizing the epidemiological situation of syphilis in the region have been determined. The necessity of interdisciplinary interaction of doctors of various specialties on early detection of patients with syphilis is indicated.

CONCLUSIONS: During the analyzed period from 2014 to 2022, in certain areas of the Ural Federal District, the current trends of syphilitic infection prevalence is characterized by multi-directional dynamics and levels of morbidity, an increase in early and late forms of syphilis in the structure of clinical forms of the disease; an increase in the registration of late latent forms of infection, cases of congenital syphilis, an increase in the incidence rate among adolescents, foreign citizens and pregnant women in the territory of the Ural Federal District.