CL307-24, A NEW ANTIBIOTIC COMPLEX FROM Saccharopolyspora aurantiaca sp. nov. II. PHYSICO-CHEMICAL AND BIOLOGICAL PROPERTIES

BERNARD FABRE; JEAN VELOURS; GILLES ETIENNE; FRÉDÉRIC LEGENDRE; GÉRARD TIRABY

doi:10.7164/antibiotics.46.1421

CL307-24, A NEW ANTIBIOTIC COMPLEX FROM Saccharopolyspora aurantiaca sp. nov.

II. PHYSICO-CHEMICAL AND BIOLOGICAL PROPERTIES

BERNARD FABRE, JEAN VELOURS, GILLES ETIENNE, FRÉDÉRIC LEGENDRE, GÉRARD TIRABY

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JOURNAL FREE ACCESS

1993 Volume 46 Issue 9 Pages 1421-1427

DOI https://doi.org/10.7164/antibiotics.46.1421

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Abstract

CL307-24I, the main component of the CL307-24 complex produced by Saccharopolyspora aurantiaca sp. nov., was found to be a potent inhibitor of yeast mitochondrial ATPase. CL307-24I displayed a high degree of activity towards some coryneform bacteria and also has been shown to possess an insecticidal activity. Its biological and physico-chemical properties clearly distinguish it from previously known ATPase inhibitors.

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