1963 年 54 巻 8 号 p. 858-882
Many clinical observations were reported on the neurogenic bladder, still there could not be found any experimental work on the relationship between the function of the urinary bladder and the injured part of the nerve innervated to it.
Hence, to clarify this problem, I have tried to examine the cystometrogram obtained on the adult dog received various section of the nerve innervated to the urinary bladder, e. g., the uni- or bi-lateral section of the pudendal, hypogastric, or pelvic nerve, and furthermore, the uni- or bi-lateral resection of the ventral, dorsal, ventral and dorsal root, and the spinal ganglion of the sacral nerve, respectively. The results obtained were as follows:
1) With the retrograde cystometry, when it was performed in the constant experimental condition, the disturbance of the vesical motility and its recovering sight were significantly analyzed.
2) The disorder of the vesical function following the unilateral section of the nerve were recovered almost to the nomal state.
3) The characteristic cystometrogram and the autonomic contraction wave were found following the bilateral section of the nerve. And we could discriminate the resected part of the nerve with the read on the cystometrogram, significantly.
4) On the cystometrogram, there was remarkable difference between the case with the bilateral section of dorsal root of the sacral nerve and the bilateral resection of spinal ganglion of that nerve.
5) With the bilateral section of the pudendal nerve, the pressure of the inner urethral sphinctor was decreased, while the inner pressure of the urinary bladder was rather increased.
6) To interpret the vesical function with the cystometrogram, the course of the curve, vesical volume and inner pressure at the micturition, contractive power of the vesical wall, and the characteristics of the autonomic contraction wave should be carefully analysed with the relation of each other.