It is generally acknowledged that the systemic factors may play a significant role in periodontal disease, although the actual factors influencing on the periodontium have not yet clearly demonstrated, so that it is hoped for the present to accumulate as much objective data as possible available for establishing the correlation between periodontal and systemic signs. For this purpose, the periodontal symptoms involved should be defined clearly in order to be comparable with other similar independent studies.
In the first paper, therefore, it was reported that the grade of the severity in periodontal diseases was better illustrated with“Russell index”, “Intensity index”, and “Extension index” based on the Russell's scoring system.
This paper reports the correlation between the clinico-chemical tests representiong systemic factors and the oral involvement as classified according to three indices mentioned-above. The clinico-chemical tests involved eighteen kinds of tests in blood and urine.
Almost all of the chemical results remained within the normal range of variations, but there was a trend that the more abnormal was the chemical results, the more severe the oral symptoms appeared.
It was interesting to find that the concentration of γ-globulin fraction in blood was elevated higher in the extensively suffering cases than in other cases when observed at the level 1.0 to 2.9 of “Intensity index”.