In previous studies, we showed that cancer pain management at community pharmacies was inadequate and that there was a significant lack of essential knowledge and experience regarding palliative care among community pharmacists. With these shortcomings in mind, we developed a training program on palliative care for community pharmacists, and evaluated the effectiveness of the program. Pharmacists working in health insurance pharmacies were divided into two groups, and the training effectiveness was measured employing Kirkpatrick's four-level evaluation model. As a result, positive effects were demonstrated in the trained group, showing marked improvements at each level, in terms of learning satisfaction, learning comprehension, behavior modification, and attainment. These findings support the validity and effectiveness of the program.