Síndrome de Lennox Gastaut. Reporte de caso clínico y minirevisión

Marlon Andrés López García; Tatiana Elizabeth Lara Abril; Lissette Carolina López Lasinquiza; Gabriela del Carmen Vargas Caiza; María Belén Vargas Congo

doi:10.56294/saludcyt2022170

Case Report

Published: 2022-12-22

DOI: https://doi.org/10.56294/saludcyt2022170

Lennox Gastaut syndrome. Case report and mini-review

Abstract

Introduction: Lennox-Gastaut syndrome is a form of childhood epilepsy that has a dramatic negative impact on the physical and developmental health of the patient. Being an age-related disorder, it is characterized by seizures, characteristic electroencephalogram, psychomotor retardation and behavioral disturbances. It is more common in males and usually begins before the age of eight years and peaks between the ages of three and five years.
Case presentation: This was a 5-year-old patient who was born prematurely product of which presented sequelae of hypoxia, who around 4 months was diagnosed with epilepsy, for which he received double antiepileptic therapy based on levetiracetam and valproic acid with partial control of his seizures until before the age of 5 years, At this time it was necessary to include a third drug to the usual therapy called clobazam, for which with the adjustment of doses until the age of 8 years he achieved a better control, however the sequelae of infantile cerebral palsy are marked.
Conclusion: It is one of the most difficult syndromes to treat and is often resistant to commonly used antiepileptic drugs. The long-term prognosis is poor; although epilepsy usually improves, complete absence of seizures is rare and, instead, psychological and psychiatric disorders worsen over time.

Keywords:

Lennox-Gastaut Syndrome,

Epileptic encephalopathy,

Antiepileptic therapy,

Intellectual disability,

How to Cite

López García MA, Lara Abril TE, López Lasinquiza LC, Vargas Caiza G del C, Vargas Congo MB. Lennox Gastaut syndrome. Case report and mini-review. Salud, Ciencia y Tecnología [Internet]. 2022 Dec. 22 [cited 2024 Jun. 1];2:170. Available from: https://revista.saludcyt.ar/ojs/index.php/sct/article/view/170

Copyright Notice

The article is distributed under the Creative Commons Attribution 4.0 License. Unless otherwise stated, associated published material is distributed under the same licence.

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