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Year 2023, Volume: 5 Issue: 2, 42 - 48, 06.09.2023

Muhammed Semih Gedik Muhammed Çiftçioğlu

https://doi.org/10.55994/ejcc.1330716
Cited By: 1

Abstract

References

  • Meltem Malkoç, Birgül Vanizor Kural. Presepsin: Sepsis Tespiti İçin Umut Verici Yeni Bir Biyobelirteç. CBU-SBED, 2021, 8(3): 553-557. DOI: 10.34087/cbusbed.887818
  • Cem Ece, İlkin Çankayali, Canan Bor, Kubilay Demirağ, Mehmet Uyar, Ali Reşat Moral. Yoğun bakım hastalarında serum CRP düzeylerinin sepsis değerlendirmesindeki yeri. Ege Tıp Dergisi / Ege Journal of Medicine 2020; 59 (3): 174-180. https://doi.org/10.19161/etd.790461
  • Sönmezer MÇ, Tülek N. Bakteriyel İnfeksiyonlarda ve Sepsiste Biyobelirteçler. Klimik Dergisi 2015; 28(3): 96-102. DOI: 10.5152/kd.2015.20
  • Seok Y, Choi JR, Kim J, Kim YK, Lee J, Song J, et al. Delta neutrophil index: a promising diagnostic and prognostic marker forsepsis. Shock. 2012 Mar;37(3):242-6. doi: 10.1097/SHK.0b013e3182454acf
  • Nilgün Eroğlu, Gülseren Şahin, Ferda Özbay Hoşnut, Gürses Şahin. Çölyak Hastalığı Diyet Uyumunda Yeni Bir Belirteç: Delta Nötrofil İndeks? Kocatepe Medical Journal 22:294-299/ Temmuz 2021. https://doi.org/10.18229/kocatepetip.864099
  • Yalan Liu, Yannan Chai, Zhihui Rong, Yan Chen. Prognostic Value of Ionized Calcium Levels in Neonatal Sepsis. Ann Nutr Metab. 2020;76(3):193-200. doi: 10.1159/000508685
  • Emine Esin Yalınbaş, Hüseyin Bilgin. Geç Neonatal Sepsis Tanısında Trombosit Parametreleri Ve Nötrofil Lenfosit Oranlarının Değerlendirilmesi. Kocatepe Tıp Dergisi. 21:104-109/2020 Özel Sayısı (1). https://doi.org/10.18229/kocatepetip.557896
  • Alkan Baylan F., Orak F., Doğaner A., Güler S., İnal Ş., Sağer H. İmmatür Granülositler; Gerçek Bakteriyemiyi Kontaminasyondan Ayırabilir Mi?. JHS. 2022; 31(2): 164-168. https://doi.org/10.34108/eujhs.860436
  • Arcagok BC, Karabulut B. Platelet to Lymphocyte Ratio in Neonates: A Predictor of Early onset Neonatal Sepsis. Mediterr J Hematol Infect Dis. 2019 Sep 1;11(1):e2019055. doi: 10.4084/MJHID.2019.055
  • Can E, Hamilcikan Ş, Can C. The Value of Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio for Detecting Early-onset Neonatal Sepsis. J Pediatr Hematol Oncol. 2018 May;40(4):e229-e232. doi: 10.1097/MPH.0000000000001059
  • Kim JW, Park JH, Kim DJ, Choi WH, Cheong JC, Kim JY. The delta neutrophil index is a prognostic factor for postoperative mortality in patients with sepsis caused by peritonitis. PLoS One. 2017 Aug 1;12(8):e0182325. doi: 10.1371/journal.pone.0182325
  • Ha SO, Park SH, Park SH, Park JS, Huh JW, Lim CM, et al. Fraction of immature granulocytes reflects severity but not mortality in sepsis. Scand J Clin Lab Invest. 2015 Jan;75(1):36-43. doi: 10.3109/00365513.2014.965736
  • Omran A, Maaroof A, Saleh MH, Abdelwahab A. Salivary C-reactive protein,mean platelet volüme and neutrophil lymphocyte ratio as diagnostic markers for neonatal sepsis. J Pediatr (RioJ).2018;94(1):82-87. DOI: 10.1016/j.jped.2017.03.006
  • Fatih Aygün. Çocuk yoğun bakımda magnezyum düzeyi prognoz ve enfeksiyon ile ilişkili midir? Online Türk Sağlık Bilimleri Dergisi 2019, Cilt 4, Sayı 1, 37-46. https://doi.org/10.26453/otjhs.442454
  • İdris Akkaş. Sepsis hastalarında eser elementlerin araştırılması/Investigation of trace elements in sepsis patients. (Tıpta Uzmanlık Tezi). Düzce Üniversitesi / Tıp Fakültesi / Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Ana Bilim Dalı, 2018, 99s.
  • Levent Döşemeci. Sepsis Ve Kan Şekeri Kontrolü. ANKEM Derg. 2006;20(Ek2):67-69.

EVALUATION AND DIAGNOSTIC EFFECTIVENESS OF HEMOGRAM, BIOCHEMISTRY AND INFLAMMATORY MARKERS (IMMATURE GRANULOCYTE, PROCALCITONIN, CRP, NLR, PLR) IN PATIENTS WITH SEPSIS

Year 2023, Volume: 5 Issue: 2, 42 - 48, 06.09.2023

Muhammed Semih Gedik Muhammed Çiftçioğlu

https://doi.org/10.55994/ejcc.1330716
Cited By: 1

Abstract

Aim
This study aimed to reveal the contributions of hemogram values and inflammatory markers involved in the pathology and progression of sepsis, and other biochemical markers such as C-reactive protein, procalcitonin, delta neutrophil index (immature granulocyte), calcium and zinc levels to the diagnosis of sepsis, and the relationship of these markers with each other.
Material and Method
This is a descriptive epidemiological study. Patients aged 18 years and over who were diagnosed with sepsis in the Emergency Department and Internal Diseases Service of Kahramanmaraş Sütçü Imam University Medical Faculty Hospital between 11.10.2022 - 11.06.2023 were prospectively included in the study.
Results
In our study, it was found that leukocyte, neutrophil, neutrophil lymphocyte ratio, platelet lymphocyte ratio, immature granulocyte, copper, phosphorus, blood glucose, C-reactive protein and procalcitonin values were high in patients with sepsis. The levels of albumin, calcium, zinc and lymphocyte were found to be low.
Conclusion
The use of biomarkers in sepsis has increasingly become important in diagnosing, following treatment, determining prognosis and predicting mortality. The biomarkers examined in this study are believed to be a reference for future studies on their use in the diagnosis, treatment and prognosis follow-up of sepsis.

Keywords

Sepsis Hemogram Biochemistry Immature granulocyte Copper Zinc

References

  • Meltem Malkoç, Birgül Vanizor Kural. Presepsin: Sepsis Tespiti İçin Umut Verici Yeni Bir Biyobelirteç. CBU-SBED, 2021, 8(3): 553-557. DOI: 10.34087/cbusbed.887818
  • Cem Ece, İlkin Çankayali, Canan Bor, Kubilay Demirağ, Mehmet Uyar, Ali Reşat Moral. Yoğun bakım hastalarında serum CRP düzeylerinin sepsis değerlendirmesindeki yeri. Ege Tıp Dergisi / Ege Journal of Medicine 2020; 59 (3): 174-180. https://doi.org/10.19161/etd.790461
  • Sönmezer MÇ, Tülek N. Bakteriyel İnfeksiyonlarda ve Sepsiste Biyobelirteçler. Klimik Dergisi 2015; 28(3): 96-102. DOI: 10.5152/kd.2015.20
  • Seok Y, Choi JR, Kim J, Kim YK, Lee J, Song J, et al. Delta neutrophil index: a promising diagnostic and prognostic marker forsepsis. Shock. 2012 Mar;37(3):242-6. doi: 10.1097/SHK.0b013e3182454acf
  • Nilgün Eroğlu, Gülseren Şahin, Ferda Özbay Hoşnut, Gürses Şahin. Çölyak Hastalığı Diyet Uyumunda Yeni Bir Belirteç: Delta Nötrofil İndeks? Kocatepe Medical Journal 22:294-299/ Temmuz 2021. https://doi.org/10.18229/kocatepetip.864099
  • Yalan Liu, Yannan Chai, Zhihui Rong, Yan Chen. Prognostic Value of Ionized Calcium Levels in Neonatal Sepsis. Ann Nutr Metab. 2020;76(3):193-200. doi: 10.1159/000508685
  • Emine Esin Yalınbaş, Hüseyin Bilgin. Geç Neonatal Sepsis Tanısında Trombosit Parametreleri Ve Nötrofil Lenfosit Oranlarının Değerlendirilmesi. Kocatepe Tıp Dergisi. 21:104-109/2020 Özel Sayısı (1). https://doi.org/10.18229/kocatepetip.557896
  • Alkan Baylan F., Orak F., Doğaner A., Güler S., İnal Ş., Sağer H. İmmatür Granülositler; Gerçek Bakteriyemiyi Kontaminasyondan Ayırabilir Mi?. JHS. 2022; 31(2): 164-168. https://doi.org/10.34108/eujhs.860436
  • Arcagok BC, Karabulut B. Platelet to Lymphocyte Ratio in Neonates: A Predictor of Early onset Neonatal Sepsis. Mediterr J Hematol Infect Dis. 2019 Sep 1;11(1):e2019055. doi: 10.4084/MJHID.2019.055
  • Can E, Hamilcikan Ş, Can C. The Value of Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio for Detecting Early-onset Neonatal Sepsis. J Pediatr Hematol Oncol. 2018 May;40(4):e229-e232. doi: 10.1097/MPH.0000000000001059
  • Kim JW, Park JH, Kim DJ, Choi WH, Cheong JC, Kim JY. The delta neutrophil index is a prognostic factor for postoperative mortality in patients with sepsis caused by peritonitis. PLoS One. 2017 Aug 1;12(8):e0182325. doi: 10.1371/journal.pone.0182325
  • Ha SO, Park SH, Park SH, Park JS, Huh JW, Lim CM, et al. Fraction of immature granulocytes reflects severity but not mortality in sepsis. Scand J Clin Lab Invest. 2015 Jan;75(1):36-43. doi: 10.3109/00365513.2014.965736
  • Omran A, Maaroof A, Saleh MH, Abdelwahab A. Salivary C-reactive protein,mean platelet volüme and neutrophil lymphocyte ratio as diagnostic markers for neonatal sepsis. J Pediatr (RioJ).2018;94(1):82-87. DOI: 10.1016/j.jped.2017.03.006
  • Fatih Aygün. Çocuk yoğun bakımda magnezyum düzeyi prognoz ve enfeksiyon ile ilişkili midir? Online Türk Sağlık Bilimleri Dergisi 2019, Cilt 4, Sayı 1, 37-46. https://doi.org/10.26453/otjhs.442454
  • İdris Akkaş. Sepsis hastalarında eser elementlerin araştırılması/Investigation of trace elements in sepsis patients. (Tıpta Uzmanlık Tezi). Düzce Üniversitesi / Tıp Fakültesi / Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Ana Bilim Dalı, 2018, 99s.
  • Levent Döşemeci. Sepsis Ve Kan Şekeri Kontrolü. ANKEM Derg. 2006;20(Ek2):67-69.
There are 16 citations in total.

Details

Primary Language English
Subjects Emergency Medicine
Journal Section Original Articles
Authors

Muhammed Semih Gedik 0000-0003-3854-4794

Muhammed Çiftçioğlu 0000-0002-8017-6502

Early Pub Date September 6, 2023
Publication Date September 6, 2023
Submission Date July 21, 2023
Acceptance Date July 26, 2023
Published in Issue Year 2023 Volume: 5 Issue: 2

Cite

APA Gedik, M. S., & Çiftçioğlu, M. (2023). EVALUATION AND DIAGNOSTIC EFFECTIVENESS OF HEMOGRAM, BIOCHEMISTRY AND INFLAMMATORY MARKERS (IMMATURE GRANULOCYTE, PROCALCITONIN, CRP, NLR, PLR) IN PATIENTS WITH SEPSIS. Eurasian Journal of Critical Care, 5(2), 42-48. https://doi.org/10.55994/ejcc.1330716
AMA Gedik MS, Çiftçioğlu M. EVALUATION AND DIAGNOSTIC EFFECTIVENESS OF HEMOGRAM, BIOCHEMISTRY AND INFLAMMATORY MARKERS (IMMATURE GRANULOCYTE, PROCALCITONIN, CRP, NLR, PLR) IN PATIENTS WITH SEPSIS. Eurasian j Crit Care. September 2023;5(2):42-48. doi:10.55994/ejcc.1330716
Chicago Gedik, Muhammed Semih, and Muhammed Çiftçioğlu. “EVALUATION AND DIAGNOSTIC EFFECTIVENESS OF HEMOGRAM, BIOCHEMISTRY AND INFLAMMATORY MARKERS (IMMATURE GRANULOCYTE, PROCALCITONIN, CRP, NLR, PLR) IN PATIENTS WITH SEPSIS”. Eurasian Journal of Critical Care 5, no. 2 (September 2023): 42-48. https://doi.org/10.55994/ejcc.1330716.
EndNote Gedik MS, Çiftçioğlu M (September 1, 2023) EVALUATION AND DIAGNOSTIC EFFECTIVENESS OF HEMOGRAM, BIOCHEMISTRY AND INFLAMMATORY MARKERS (IMMATURE GRANULOCYTE, PROCALCITONIN, CRP, NLR, PLR) IN PATIENTS WITH SEPSIS. Eurasian Journal of Critical Care 5 2 42–48.
IEEE M. S. Gedik and M. Çiftçioğlu, “EVALUATION AND DIAGNOSTIC EFFECTIVENESS OF HEMOGRAM, BIOCHEMISTRY AND INFLAMMATORY MARKERS (IMMATURE GRANULOCYTE, PROCALCITONIN, CRP, NLR, PLR) IN PATIENTS WITH SEPSIS”, Eurasian j Crit Care, vol. 5, no. 2, pp. 42–48, 2023, doi: 10.55994/ejcc.1330716.
ISNAD Gedik, Muhammed Semih - Çiftçioğlu, Muhammed. “EVALUATION AND DIAGNOSTIC EFFECTIVENESS OF HEMOGRAM, BIOCHEMISTRY AND INFLAMMATORY MARKERS (IMMATURE GRANULOCYTE, PROCALCITONIN, CRP, NLR, PLR) IN PATIENTS WITH SEPSIS”. Eurasian Journal of Critical Care 5/2 (September 2023), 42-48. https://doi.org/10.55994/ejcc.1330716.
JAMA Gedik MS, Çiftçioğlu M. EVALUATION AND DIAGNOSTIC EFFECTIVENESS OF HEMOGRAM, BIOCHEMISTRY AND INFLAMMATORY MARKERS (IMMATURE GRANULOCYTE, PROCALCITONIN, CRP, NLR, PLR) IN PATIENTS WITH SEPSIS. Eurasian j Crit Care. 2023;5:42–48.
MLA Gedik, Muhammed Semih and Muhammed Çiftçioğlu. “EVALUATION AND DIAGNOSTIC EFFECTIVENESS OF HEMOGRAM, BIOCHEMISTRY AND INFLAMMATORY MARKERS (IMMATURE GRANULOCYTE, PROCALCITONIN, CRP, NLR, PLR) IN PATIENTS WITH SEPSIS”. Eurasian Journal of Critical Care, vol. 5, no. 2, 2023, pp. 42-48, doi:10.55994/ejcc.1330716.
Vancouver Gedik MS, Çiftçioğlu M. EVALUATION AND DIAGNOSTIC EFFECTIVENESS OF HEMOGRAM, BIOCHEMISTRY AND INFLAMMATORY MARKERS (IMMATURE GRANULOCYTE, PROCALCITONIN, CRP, NLR, PLR) IN PATIENTS WITH SEPSIS. Eurasian j Crit Care. 2023;5(2):42-8.

Cited By

Prognostic Biomarkers in Sepsis
Eurasian Journal of Critical Care
https://doi.org/10.55994/ejcc.1388848
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