Crimean-Congo Hemorrhagic Fever (CCHF): An Emerging Disease in Afghanistan

Ajmal Khosti; Sakhi Sardar; Sherzad Gulsharif

doi:10.55544/ijrah.3.1.7

Authors

Ajmal Khosti Assistant Professor, Department of Para Clinic, Faculty of Veterinary Science, Shaikh Zayed University, Khost, AFGHANISTAN.
Sakhi Sardar Assistant Professor, Department of Patholgy, Faculty of Medical, Skaikh Zayed University, Khost, AFGHANISTAN.
Sherzad Gulsharif Assistant Professor, Department of Surgery, Faculty of medical, Shaikh Zayed University, Khost, AFGHANISTAN.

DOI:

https://doi.org/10.55544/ijrah.3.1.7

Keywords:

Crimean-Congo Hemorrhagic Fever (CCHF), Viral disease, Afghanistan

Abstract

Crimean-Congo hemorrhagic fever (CCHF) seems to be a severe viral infection that is spreading throughout Afghanistan. The first case of CCHF was recorded in March 1998 in Takhar province, located in the country’s north. And since then, multiple new cases and outbreaks have occurred over the years and continue to do so now. CCHF is a viral disease that is transmitted to humans mostly by hard tick bites or direct contact with the blood of infected animals. In Afghanistan, the prevalence of CCHF outbreaks has grown dramatically around Eid-ul-Adha. The primary symptom of this fatal disease is bleeding. There is no cure for CCHF at the moment, but the antiviral drug Ribavirin is used to treat it. This disease presently lacks a commercially accessible vaccine. The disease is recommended to be controlled through preventative measures such as Avoiding insect bites and coming into touch with the blood of a suspicious animal are just a few of the precautions that can be taken.

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References

Ali, K. N., Anushree, J., Reenu, C., Mohammad, A., & Kamal, K. (2011). Crimean Congo Hemorrhagic Fever - An Article Review. International Research Journal of Pharmacy, 2(5), 33–44.

Appannanavar, S. B., & Mishra, B. (2011). An update on crimean congo hemorrhagic fever. Journal of Global Infectious Diseases, 3(3), 285–292. https://doi.org/10.4103/0974-777X.83537

Aradaib, I. E., Erickson, B. R., Mustafa, M. E., Khristova, M. L., Saeed, N. S., & Elageb, R. M....Nichol, S. T. (2010). Nosocomial Outbreak of Crimean-Congo Hemorrhagic Fever,. Sudan. Emerging Infectious Diseases, 16(5), 837–839. https://doi.org/10.3201/

Aslam, S., Latif, M. S., Daud, M., Rahman, Z. U., Tabassum, B., Riaz, M. S., Khan, A., Tariq, M., & Husnain, T. (2016). Crimean-Congo hemorrhagic fever: Risk factors and control measures for the infection abatement. Biomedical Reports, 4(1), 15–20.

Athar, M. N., Baqai, H. Z., Ahmad, M., M.A., K., Bashir, N., Ahmad, A. M., Balouch, A. H., & Bashir, K. (2005). Crimean-Congo Hemorrhagic Fever Outbreak in Rawalpindi, Pakistan, Contact Tracing and Risk Assessment. American Journal of Tropical Medicine and Hygiene, 72(4), 471–473.

Bajpai, S., & Nadkar, M. Y. (2011). Crimean Congo Hemorrhagic Fever: Requires Vigilance and Not Panic. Journal of the Association of Physicians of India, 59, 164–167.

Bente, D. A., Forrester, N. L., Watts, D. M., McAuley, A. J., Whitehouse, C. A., & Bray, M. (2013). Crimean-Congo Hemorrhagic Fever: History, epidemiology, pathogenesis, clinical syndrome and genetic diversity. Antiviral Research, 100(1), 159–189. http://dx.doi.org/10.1016/j.antiviral.%0A2013.07.006

Burt, F. J., Leman, P. A., Smith, J. F., & Swanepoel, R. (1998). The use of a reverse transcription-polymerase chain reaction for the detection of viral nucleic acid in the diagnosis of Crimean-Congo Haemorrhagic Fever. Journal of Virological Methods, 70(2), 129–137. http://dx.doi.org/10.1016/%0AS0166-0934(97)00182-1%0A

Burt, F. J., Swanepoel, R., Shieh, W. J., Smith, J. F., Leman, P. A., Greer, P. W., Coffield, L. M., Rollin, P. E., Ksiazek, T. G., Peters, C. J., & Zaki, S. R. (1997). Immunohistochemical and in situ localization of Crimean-Congo hemorrhagic fever (CCHF) virus in human tissues and implications for CCHF pathogenesis. Archives of Pathology and Laboratory Medicine, 121(8), 839–846.

Buttigieg, K. R., Dowall, S. D., Findlay-Wilson S., Miloszewska, A., Rayner, E., Hewson, R., & Carroll, M. W. (2014). A Novel Vaccine against Crimean- Congo Haemorrhagic Fever Protects 100% of Animals against Lethal Challenge in a Mouse Model. PLoS One, 9(3), 91516.

Gonzalez, J. P., Camicas, J. L., Cornet, J. P., O., F., & Wilson, M. L. (1992). Sexual and transovarian transmission of Crimean-Congo Haemorrhagic Fever Virus in Hyalomma truncatum ticks. Research in Virology, 143(1).

Goodman, L. J., David, T. D., & Sonen, S. E. (2005). “Tick-Borne Disease of Humans.” ASM Press, Washington, D.C.

Goswami, T. K., Singh, D. K., Saminathan, M., Verma, A. K., & Dhama, K. (2014). An Emerging Threat of Crimean Congo Hemorrhagic Fever: Call for Preparedness. Advances in Animal and Veterinary Sciences. 2(1), 8–14.

Hasan, Z., Atkinson, B., Jamil, B., Samreen, A., Altaf, L., & Hewson, R. (2014). Diagnostic Testing for Hemorrhagic Fevers in Pakistan: 2007-2013. The American Journal of Tropical Medicine and Hygiene, 91(6), 1243–1246.

Hatami, H., Qaderi, S., & Omid, A. (219 C.E.). Investigation of Crimean-Congo hemorrhagic fever in patients admitted in Antani Hospital, Kabul, Afghanistan, 2017–2018. Int J Preventive Med, 10(1).

Hoogstraal, H. (1979). The Epidemiology of Tick-Borne Crimean-Congo Hemorrhagic Fever in Asia, Europe, and Africa. Journal of Medical Entomology, 5(4), 307–417. http://dx.doi.org/10.1093/

Hussain, Q., Shaikh, B. H., Bhutto, A. R., & M., S. (2016). An Unusual Case of Crimean Congo Hemorrhagic Fever: Prolonged Bleeding with Successful Recovery. Journal of the College of Physicians and Surgeons Pakistan, 26(2), 151–153. http://dx.doi.org/10.1016/j.%0Avirol.2003.09.042

Kemp, A., Msimang, V., Weyer, J., & Paweska, J. T. (2014). Crimean-Congo Haemorrhagic Fever and Tick bite Fever in South Africa, 2012-2014. National Institute for Communicable Diseases, Infectious Diseases Bulletin, 12(3), 59–62.

Keshtkar-Jahromia, M., Kuhnb, J. H., I., C., Bradfuted, S. B., Jahrlingb, P. B., & Bavari, S. (2011). Crimean-Congo hemorrhagic fever: Current and future prospects of vaccines and therapies. Antiviral Research, 90(2), 85–92.

Leblebicioglu, H., Sunbul, M., Memish, Z. A., Tawfiq, J. A. A., Bodur, H., Ozkul, A., Gucukoglu, A., & Chinikar, S., Hasan, Z. (2015). Consensus report: Preventive measures for Crimean-Congo Hemorrhagic Fever during Eid-al-Adha festival. International Journal of Infectious Diseases, 38, 9–15. http://dx.doi.org/10.1016/j.ijid.2015.06.029

Mamuchishvili, N., Salyer, S. J., Stauffer, K., Geleishvili M., Zakhashvili, K., & Morgan, J. (2015). Notes from the field: Increase in reported Crimean- Congo hemorrhagic fever cases--country of Georgia, 2014. Morbidity and Mortality Weekly Report, 64(8), 228–229.

Mertens, M., Schmidt, K., Ozkul, A., & Groschup, M. H. (2013). The impact of Crimean-Congo Hemorrhagic Fever Virus on public health. Antiviral Research, 98(2), 248–260.

Mofleh, J., & Ahmad, A. (2012). Crimean-Congo haemorrhagic fever outbreak investigation in the Western Region of Afghanistan in 2008. EMHJ-East Mediterr Health J, 18(5), 522–526.

MOP, H. (2018). National Disease Surveillance and Response data. Kabul, Afghanistan.

Morrill, J. C., Oliman, A. K., Imam, I. Z., B.A., B., Moussa, M. I., & Watts, D. M. (1990). Serological evidence of Crimean-Congo Haemorrhagic Fever viral infection among camels imported into Egypt. The Journal of Tropical Medicine and Hygiene, 93(3), 201–204.

Mourya, D. T., Yadav, P. D., Shete, A., MajumdarT.D., Kanani, A., Kapadia, D., Chandra, V., Kachhiapatel, A.J., Joshi, P. T., Upadhyay, K. J., Dave, P., & Raval, D. (2014). Serosurvey of Crimean-Congo Hemorrhagic Fever Virus in Domestic Animals, Gujarat, India, 2013. Vector-Borne and Zoonotic Diseases, 14(9), 690–692.

Nabeth, P., Cheikh, D. O., Lo, B., Faye, O., I.O., V., Niang, M., Wague, B., Diop, D., Diallo, M., Diallo, B., Diop, O. M., & Simon, F. (2004). Crimean-Congo hemorrhagic fever, Mauritania. Emerging Infectious Diseases, 10, 2143–2149.

OIE, O. I. E. (2014). World Health Organization (WHO), Food and Agriculture Organization of the United Nations (FAO), 2009: Partners Available at:

Ozsoy, S., Gokmen, A., Ozdemir, M., B., A., Korkusuz, I., & Javan, G. T. (2015). Medical examiners and Crimean-Congo hemorrhagic fever contamination risk. Journal of Forensic and Legal Medicine, 36, 32–36.

Peyrefitte, C., Marianneau, P., Tordo, N., & Bouloy, M. (2015). Crimean-Congo Haemorrhagic Fever Revue scientifique et technique. (International Office of Epizootics), 34(2), 391–401.

Saleem, J., Usman, M., Nadeem, A., Sethi, S. A., & Salman, M. (2009). Crimean-Congo hemorrhagic fever: a first case from Abbottabad, Pakistan. International Journal of Infectious Diseases, 13, 121–123. http://dx.doi.org/10.1016/j.ijid.2008.07.023

Shayan, S., Bokaean, M., Shahrivar, M. R., & Chinikar, S. (2015). Crimean-Congo Hemorrhagic Fever. Laboratory Medicine, 46(3), 180–189.

Swanepoel, R., Gill, D. E., Shepherd, A. J., P.A., L., Mynhardt, J. H., & Harvey, S. (1989). The Clinical Pathology of Crimean-Congo Hemorrhagic Fever. Clinical Infectious Diseases, 11(4), 794–800. http://dx.doi.org/10.1093/clinids/11.%0ASupplement_4.S794%0A

Tantawi, H. H., Al-Moslih, M. I., Al-Janabi, N. Y., Al-Bana, A. S., Mahmud, M. I., Jurji, F., Y., M.S., Al-Ani, F., & Al-Tikriti, S. K. (1980). Crimean-Congo Haemorrhagic Fever virus in Iraq: isolation, identification and electron microscopy. Acta Virologica, 24(6), 464–467.

Tishkova, F. H., Belobrova, E.A., Valikhodzhaeva M., Atkinson, B., & Hewson, R., M. M. (2012). Crimean-Congo Hemorrhagic Fever in Tajikistan. Vector-Borne and Zoonotic Diseases, 12(9), 722–726. http://dx.doi.org/10.1089/%0Avbz.2011.0769

Turell, M. J. (2007). Role of Ticks in the Transmission of Crimean-Congo Hemorrhagic Fever Virus. In: Ergonul, O., Whitehouse,C. A (eds), Crimean-Congo Hemorrhagic Fever: A Global Perspective, 1, 143–154.

Vashakidze, E., & Mikadze, I. (2015). Epidemiology, Clinical and Laboratory Features of Crimean-Congo Hemorrhagic Fever in Georgia. Georgian Medical News, 54, 54–58.

Vorou, R. M. (2009). Crimean-Congo Hemorrhagic Fever in Southeastern Europe. International Journal of Infectious Diseases, 13, 659–662.

Wasfi, F., Dowall, S., Ghabbari, T., Bosworth, A., Chakroun, M., Varghese, A., Tiouiri, H., B., Jemaa, M., Znazen, A., Hewson, R., ZhiouaE., & Letaief, A. (2016). Sero-epidemiological survey of Crimean-Congo hemorrhagic fever virus in Tunisia. Parasite (Paris, France.), 23(10).

WHO, W. H. O. (2014). 2014: Partners Available at: http://www.emro.who.int/ (accessed 19 March 2016).

Zavitsanou, A., Babatsikou, F., & Koutis, C. (2009). Crimean Congo Hemorrhagic Fever: An Emerging Tick- Borne Disease. Health Science Journal, 3(1), 10–18.