It has been recognized that serum lipids play the important rolls to the development of atherosclerosis, and many studies about hyperlipidemia have been made from the aspects of the lipid metabolism, epidemiology and pathology.
Ninety ambulatory patients, in Urban residents consist of 25 male and 25 female with age range of 30 to 90 year-old, and suburban residents (fishing village) consist of 15 male and 25 female with age range of 34 to 80 year-old, have been followed up for full 2 years, from April 1973 to March 1975, to survey the serum total cholesterol levels and its seasonal changes between the two groups and to check relationship to coronary heart disease, hypertension, obesty and other diseases.
1) The serum total cholesterol level of patients in urban and suburban residents were essentially unchanged (Fig 1).
In large city; 235.8±35.9mg/dl→204.8+33.3mg/dl
In fishing village; 206.8±37.0mg/dl→217.0+39.1mg/dl
2) There were no remarkable changes in serum total cholesterol levels depended upon basic diseases.
3) Fifty-five of ninety (60 percent) showed unstable levels of serum total cholesterol (Labile group).
4) Thirty-five out of ninety (40 percent) showed nonseasonal change (nonseasonal labile group).
These results indicate that it is neccessary to check the serum cholesterol levels more frequently to decide if hyperlipemia exists or not.