Literature review on targeted therapies in management of solid tumours

Madhavi Venkata Bellala, Srikanth Dikkala, Tulika Tyagi, Prithviraj Bellala, Rishik Bellala and Ravishankar Bellala *

Omega Hospital, Arilova, Health City, Chinagadili, Visakhapatnam, Andhra Pradesh 530040 India.
 
Review
International Journal of Scientific Research Updates, 2022, 03(01), 010–021.
Article DOI: 10.53430/ijsru.2022.3.1.0021
Publication history: 
Received on 05 December 2021; revised on 12 January 2022; accepted on 14 January 2022
 
Abstract: 
Purpose: To depict the emergence of targeted therapies that have led to distinguished breakthrough in the management of cancer.
Methods: The literature was systematically reviewed, based on their evolution and their use with understanding on the adverse effects.
Results: Cancer genomics and model systems have enabled new therapeutic strategies. Targeted therapy is a novel cancer treatment that targets the specific molecular targets associated with cancer, where as chemotherapy drugs act on rapidly dividing normal and cancer cells. Most types of targeted therapies are designed to interact with the specific target. Targeted therapies can block or turn off signals thus control growth, division of cancer cells. Most targeted therapies are either small-molecule drugs or monoclonal antibodies. Targeted therapies are the cornerstone of precision medicine that uses information about the genes and protein. This review will discuss various targeted therapies in management of solid tumors.
 
Keywords: 
Targeted therapy for solid tumours; Targeted therapy drugs; Molecular Targeted therapy; Precession Cancer treatment; Molecular Medicine for cancer
 
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