The utilization of plant extracts/biomaterials for the green synthesis of nanoparticles, their biological activity and mode of action

Ali Esmail Al-Snafi 1, Hussein Ali Hussein Al-Sa'idy 2, * and Hussein Kamil Hamid 3

1 Department of Pharmacology, College of Medicine, University of Thi-Qar, 64001, Iraq.
2 Department of Environment and Pollution, Marshes research center, University of Thi-Qar, 64001, Iraq.
3 College of Pharmacy, National University of Science and Technology, Thi-Qar, 64001, Iraq.
 
Review Article
Open Access Research Journal of Biology and Pharmacy, 2022, 06(01), 017–046.
Article DOI: 10.53022/oarjbp.2022.6.1.0063
Publication history: 
Received on 04 August 2022; revised on 09 September 2022; accepted on 11 September 2022
 
Abstract: 
Nanotechnology is one of the modern approaches that has found access to the medicinal as well as pharmaceutical uses where the nanoparticles of the nobel as well as other metals nanoparticles and their oxides have been reported to exploite various biological activities particularly antimicrobial besides antineoplastic activities. In addition, metal/metal oxides nanoparticles have also been proposed to have diagnostic applications in radioscanning of neoplastic diseases besides pharmaceutical application in neoplastic drugs delivery. Green/eco-friendly synthesis of these nanoparticles using biomaterials is considered as an innovatory approach for their production through which attaining economically beneficial along with drastic polluting methods avoidance advantages. In this context, plants extracts are increasingly finding the way for their production. In this survey, the green chemical synthesis approaches of nanoparticals of different metals and their oxides, their medical uses and biological activities, particularly antimicrobial mechanism of silver nanoparticles, as well as antineoplastic activity are discussed. The outcomes of this survey encourage us to conclude the feasibility of investment in the investigations in this approach.
 
Keywords: 
Plant; Extracts; Biomaterials; Green; Nanoparticles; Biological activity
 
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