Functional indices of vitamin D status and consequences of vitamin D deficiency

Abstract: Serum 25-hydroxyvitamin D₃ [25(OH)D₃] concentrations are currently recognized as the functional status indicator for vitamin D. Evidence is reviewed that shows that serum 25(OH)D₃ concentrations of < 80 nmol/L are associated with reduced calcium absorption, osteoporosis, and increased fracture risk. For typical older individuals, supplemental oral intakes of ~1300 IU/d are required to reach the lower end of the optimal range. Evidence of substantial problems in routine clinical measurement of serum 25(OH)D₃ concentrations among patients is cited. There is great need for standardization and improved reproducibility and sensitivity of measurements of serum 25(OH)D₃ concentrations.

Keywords: Rickets, osteomalacia, osteoporosis, calcium absorption, fractures, serum 25-hydroxyvitamin D_3.

Title: Functional indices of vitamin D status and consequences of vitamin D deficiency

Author: FAHAD ABDULAZIZ ALKHARAAN, NAWAF TURKY ALENIZI, MOHAMMED HADI ALHABABI, NORA MUNAHI ALMUTAIRI, Abdullah Abdulrzaq Aljuwayi

International Journal of Life Sciences Research

ISSN 2348-313X (Print), ISSN 2348-3148 (online)

Vol. 10, Issue 4, October 2022 - December 2022

Page No: 92-96

Research Publish Journals

Website: www.researchpublish.com

Published Date: 28-December-2022

DOI: https://doi.org/10.5281/zenodo.7488592

Paper Download Link (Source)

https://www.researchpublish.com/papers/functional-indices-of-vitamin-d-status-and-consequences-of-vitamin-d-deficiency