Published online Dec 31, 1994.
https://doi.org/10.4070/kcj.1994.24.6.877
Efficacy of Diet Therapy in Korea Hypercholesterolemic Patients
Abstract
Background
Although diet therapy is the standard initial treatment for hypercholesterolemia, the efficacy of diet therapy in Korean hypercholesterolemic patients never been investigated . This study was designed to evaluate the efficacy of diet therapy for hypercholesterolemia.
Methods
One hundred seventeen outpatients with hypercholesterolemia were educated individualized diet therapy which is low in fat, cholesterol and high fiber. After three and six month, we assessed the changes of plasma lipids, apolipoproteins, body weight and the adherence to diet therapy.
Results
After 3 months of the diet therapy, there were significant reductions in total cholesterol(-11.8%), LDL-C(-14.5%), HDL-C(-3.9%), Apo(-5.4%), TC/HDL-C(-7.3%), Apo B /Apo A1(-7.7%) and weight(-3.1%). After 6 months of the diet therapy, there were significant reductions in total cholesterol(-10.7%), LDL-C(-14.0%), TC/HDL-C(-9.1%), Apo B/Apo A1(-7.7%) and weight(-2.3%). In this study 77% of the subjects had experienced improvement in their plasma LDL-C. Nonrespondents were older and had more female patients than respondents significantly.
Conclusion
Diet therapy in Korean hypercholesterolemic patients is effective for reductions of total cholesterol and LDL-C.
