The Immunizing Effect to M. Tuberculosis in Rabbits Vaccinated with Unclassified Mycobacteria |
Kyung Soo Kim, Wun Ki Lee, Doo Hi Kim |
Department of Preventive Medicine, School of Medicine, Kyungpook University, Taegu, Korea |
가토에 있어서 Unclassified Mycobacteria의 결핵균에 대한 면역적 효과 |
김경수, 이원기, 김두희 |
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Abstract |
The present study was carricd out to determine the immunizing effect of six strains of unclassified mycobacteria saprophytes and BCG, to M. tuberculosis in rabbits which were vaccinacd with the above three groups of strain.
The unclassified mycobacteria was isolated from the patients’ sputa who were clinically dingnosed as
having the so-called active pulmonary tuberculosis in Korea. The saprophytic strains includes M. for-tuitum, M. smegmatis and acid-fast bacilli isolated from soil. The result obtained is summarized as follow: BCG is more effective in immunity against infection with M. tuberculosis among the above three groups, and unclassified mycobacteria was found to have a partial immunity to M. tuberculosis, while saprophytes failed to show protective ability against M. tuberculosis as seen in the control group. |
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