Synthesis and Characterization of Biocompatible Fe3O4 for Use in Cell Hyperthermia

Fernanda A. Sampaio da Silva; Edwin E. G. Rojas; Girley F. Rodrigues; Bruno F.A. da Silva; Marcos Flavio de Campos

doi:10.4028/www.scientific.net/MSF.775-776.476

Paper Titles

Influence of Clay Content in Membrane Morphology of Polymer Polyamide 6.6/Montmorillonite Clay
p.455

Obtaining of Polyamide 6.6 Plane Membrane Application in Oil-Water Separation
p.460

Nanocomposites Obtained by Montmorilonite Clay Additivation in P3 (HB-8%HV)
p.465

Evaluation of Attapulgite Clay Content from Piauí in Sorption Characterization of Water in the Polyester Matrix Composites
p.471

Synthesis and Characterization of Biocompatible Fe₃O₄ for Use in Cell Hyperthermia
p.476

Microstructural Evolution of a F138 Austenitic Stainless Steel after Deformation by ECAP and HPT
p.482

Morphological Comparison of PEI and PES Nanocomposite Membranes with Bentonite Clay
p.487

Analysis of the Efficiency of Surface Treatment of Bentonite Clay for Application in Polymeric Membranes
p.493

Study of Morphology Membrane of Polymeric Nanocomposites Obtained by Phases Inversion
p.498

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Synthesis and Characterization of Biocompatible Fe₃O₄ for Use in Cell Hyperthermia

Abstract:

Malignant tumors are caused by uncontrolled multiplication of cells in the body. It is possible to stop the growth of atypical cells by overheating (hyperthermia). By the magnetization process of magnetite nanoparticles, energy is dissipated as heat (Joule effect), producing increase of temperature. This causes the rupture of cancer cells. In this work, magnetic nanoparticles were synthesized by coprecipitation method and coated by biocompatible material (chitosan or castor oil). The samples showed required characteristics of nanocrystallinity, superparamagnetism and biocompatibility. This was deduced from hysteresis curve, thermal analysis and X-ray Diffraction data. Thus, the nanocomposite exhibits excellent features for use in vivo.