Synthesis of Poly(ε-Caprolactone)-Organosiloxane Hybrid Containing Amine Group

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Abstract:

Novel poly(ε-caprolactone)-organosiloxane hybrid containing amine group was synthesized through sol-gel method. Triethoxysilane end-capped poly(ε-caprolactone) was prepared by reaction with α,ω-hydroxyl poly(ε-caprolactone) and 3-isocyanatopropyl triethoxysilane. It was then hydrolyzed and co-condensed with aminopropyl triethoxysilane through sol-gel method. The success of hybridization was evaluated by FT-IR by new formation of siloxane group. Osteoblast-like cell responses were assessed on this new hybrid material for the potential application as a bone tissue engineering scaffold. The cell responses were compatible with those on pure poly(ε-caprolactone) used as a control.

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Periodical:

Key Engineering Materials (Volumes 330-332)

Pages:

1277-1280

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Online since:

February 2007

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[1] Rhee S. H., Lee Y. K., Lim B. S., Yoo J. J., Kim H. J.: Biomacromolecules Vol. 5 (2004), p.1575.

Google Scholar

[2] Rhee S. H.: J Biomed Mater Res Vol. 67A (2003), p.1131.

Google Scholar

[3] Rhee S. H.: Biomaterials Vol. 24 (2003), p.1721.

Google Scholar

[4] Rhee S. H.: Biomaterials Vol. 25 (2004), p.1167.

Google Scholar

[5] Rhee S. H., Choi J. Y., Kim H. M.: Biomaterials Vol. 23 (2002), p.4915.

Google Scholar

[6] Yoo J. J., Rhee S. H.: J Biomed Mater Res Vol. 68A (2004), p.401.

Google Scholar