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Synthesis of Poly(ε-Caprolactone)-Organosiloxane Hybrid Containing Amine Group
Abstract:
Novel poly(ε-caprolactone)-organosiloxane hybrid containing amine group was synthesized through sol-gel method. Triethoxysilane end-capped poly(ε-caprolactone) was prepared by reaction with α,ω-hydroxyl poly(ε-caprolactone) and 3-isocyanatopropyl triethoxysilane. It was then hydrolyzed and co-condensed with aminopropyl triethoxysilane through sol-gel method. The success of hybridization was evaluated by FT-IR by new formation of siloxane group. Osteoblast-like cell responses were assessed on this new hybrid material for the potential application as a bone tissue engineering scaffold. The cell responses were compatible with those on pure poly(ε-caprolactone) used as a control.
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1277-1280
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Online since:
February 2007
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