Basicity, Water Solubility and Intrinsic Viscosity of Carboxymethyl Chitosan as a Biofunctional Material

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Abstract:

The basicity, water solubility, intrinsic viscosity and molecular weight of carboxymethyl chitosan (CM-chitosan) were investigated. The solution pH remained at about 9.2 at the concentration of higher than 2.0 g/L. The isoelectric point of CM-chitosan was about 4.5 of pH, and the solubility of CM-chitosan at the solution pH of 2.0 to 6.0 was lower than 5 g/L. The acetic acid could be replaced by hydrochloric acid as solvent for the viscosity-average molecular weight determination of chitosan. The intrinsic viscosity values of CM-chitosan have significant differences in acidic and alkaline conditions. The viscosity-average molecular weight of CM-chitosan was (3.8 ± 0.2) × 105, consistent with that of product chitosan of blank test.

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507-510

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June 2012

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