Formation of Calcium-Deficient Hydroxyapatite via Hydrolysis of Nano-Sized Pure α-Tricalcium Phosphate

Linda Vecbiskena; K. Gross; Una Riekstina; C.K. Thomas Yang

doi:10.4028/www.scientific.net/AMR.1117.201

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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 1117Formation of Calcium-Deficient Hydroxyapatite via...

Formation of Calcium-Deficient Hydroxyapatite via Hydrolysis of Nano-Sized Pure α-Tricalcium Phosphate

Abstract:

Nano-sized pure α-tricalcium phosphate (α-TCP) fabricated by a novel synthesis approach shows great potential for a faster transformation into calcium-deficient hydroxyapatite (CDHA) than conventionally prepared α-TCP. In this work, amorphous tricalcium phosphate precursors were precipitated and treated with a solvent (water or ethanol), and dried (freeze-dried and oven-dried) before heating at 775 °C. Nanosized α-TCP powders were investigated for their phase composition and crystallinity, particle shape and size, reactivity and cellular biocompatibility. Reaction with water showed faster CDHA formation for freeze-dried powder, at 6 hours, compared to ethanol treated powders, whereas a higher biocompatibility was found for pure α-TCP.

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Periodical:

Advanced Materials Research (Volume 1117)

Pages:

201-204

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.1117.201

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Online since:

July 2015

Authors:

Linda Vecbiskena*, K. Gross, Una Riekstina, C.K. Thomas Yang

Keywords:

Amorphous Calcium Phosphate, Calcium-Deficient Hydroxyapatite, Cell Response, α-Tricalcium Phosphate

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