We have studied 53 resected cases of gallbladder carcinoma to clarify prognosis-regulating factors. All pathologic factors including dysplasia were examined first in 3 groups categorized according to depth of invasion, then in ss-cancer-group, where further consideration was given in relation to survival rates. The probability of finding dysplasia was higher as invasion was less severe (p<0.01). As for ss-cancergroup study, the results were as follows: outcome was significantly worse in cases of positive lymphatic invasion (p<0.05), positive bile duct invasion (p<0.01). and extensive subserosal invasion (p<0.01). Carcinoma associated with dysplasia showed a better outcome (p<0.01). Also, better outcome was assumed in cases of papillary adenocarcinoma (pap) and negative lymph node invasion. Regarding INF, results were ranked with α, β, and γ in this order, and for the depth of subserosal invasion, ss₁, ss₂, and ss₃. No significant relation was found in factors such as macroscopic form, tumor site, desmoplasia, venous invasion, perineural invasion and hepatic infiltration. The fact that gallbladder carcinoma associated with dysplasia showed a good outcome suggests that whether dysplasia is found or not can be a new prognosis regulating factor.