A case of spindle cell carcinoma of the breast with liver metastasis is reported. A 48-year-old woman had noticed a left breast tumor in June 1998. She was admitted to the hospital because of rapid enlargement of the tumor on September 4, 1998. A 18×13×10cm tumor was palpated at the entire left breast, that had na ulcerative region at the B area. The tumor was diagnosed as a malignant tumor by a needle biopsy, but the histological type did not demonstrated. Preoperative study revealed a solitary tumor at the lateral segment of the liver. Modified radical mastectomy was performed with a preoperative diagnosis of malignant breast tumor with liver metastasis on September 21, 1998. Postoperative histopathological examination revealed spindle cell carcinoma with axillaly lymph node metastasis. No systemic metastasis without liver metastasis was revealed, and so a lateral segmental resection of the liver was performed. A histopathological examination revealed a metastatic liver tumor of the breast cancer. The patient received hormonotherapy and chemotherapy postoperatively and she has been from recurrence, as of 8 months after the operation.