A review of Leaves and Seeds Moringa oleifera Extract: The potential Moringa oleifera as Antibacterial, Anti-Inflammatory, Antidiarrhoeal, And Antiulcer Approaches To Bacterial Gastroenteritis

Arga Setyo Adji; Nabila Atika; Yemima Billyana Kusbijantoro; Atiyatum Billah; Astrid Putri; Fitri Handajani

doi:10.3889/oamjms.2022.8894

Authors

Arga Setyo Adji Faculty of Medicine, Hang Tuah University, Surabaya, Indonesia https://orcid.org/0000-0002-0188-0500
Nabila Atika Faculty of Medicine, Hang Tuah University, Surabaya, Indonesia https://orcid.org/0000-0003-1893-3565
Yemima Billyana Kusbijantoro Faculty of Medicine, Hang Tuah University, Surabaya, Indonesia https://orcid.org/0000-0002-1235-5744
Atiyatum Billah Faculty of Medicine, Hang Tuah University, Surabaya, Indonesia https://orcid.org/0000-0002-3436-9004
Astrid Putri Faculty of Medicine, Hang Tuah University, Surabaya, Indonesia https://orcid.org/0000-0002-8074-5832
Fitri Handajani Department of Biochemistry, Faculty of Medicine, Hang Tuah University, Surabaya, Indonesia https://orcid.org/0000-0001-8302-0151

DOI:

https://doi.org/10.3889/oamjms.2022.8894

Keywords:

Diarrhea, Gastroenteritis, Antibacterial, Antiulcer, Anti-Inflammation, Moringa oleifera

Abstract

BACKGROUND: Bacterial gastroenteritis is a disease in the tropics in the form of inflammation of the stomach and intestines due to several bacteria, such as Salmonella, Campylobacter, Shigella, Escherichia coli, Vibrio, Yersinia, and Listeria with symptoms of diarrhea without or with vomiting and frequent fever. Gastroenteritis is a global disease with the highest prevalence in the agricultural community, especially farmers and fishermen.

AIM: This research is to determine the potential of leaf and seed extract Moringa oleifera as an alternative therapy for bacterial gastroenteritis.

METHODS: A literature review approach derived from the analysis and synthesis of various related references is used. The author selects journals full text and books published in the last ten years maximum through several databases, namely PubMed, Google Scholar, ScienceDirect, and Cochrane with the keywords: diarrhea, gastroenteritis, antibacterial, antiulcer, anti-inflammation, and M. oleifera.

RESULTS: Seed and leaf extract M. oleifera played a role in preventing some of the effects of the pathogenesis of diarrhea due to bacterial infection. Methanol, N-hexane, ethyl acetate, flavonoids, phenols, saponins, alkaloids, tannins, and steroids from seed and leaf extract M. oleifera have antibacterial effects. The content of quercetin has an anti-inflammatory effect. The content of tannins, flavonoids, and alkaloids has antidiarrheal activity. The content of ethanol and tannins has an antiulcer effect. This potential can help cure patients with bacterial gastroenteritis.

CONCLUSION: Leaf and seed extract of M. oleifera has good antibacterial, anti-inflammatory, antiulcer, and antidiarrheal potential for the treatment of bacterial gastroenteritis.

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