色谱

色谱 ›› 2018, Vol. 36 ›› Issue (8): 822-826.DOI: 10.3724/SP.J.1123.2018.03011

• 技术与应用 • 上一篇    下一篇

常规离子色谱系统-电容耦合非接触式电导检测器的构建

陈小花1, 侯彦杰1, 杨丙成1, 艾雷2   

  1. 1. 华东理工大学药学院, 上海 200237;
    2. 苏州明昊色谱技术有限公司, 江苏 苏州 215500
  • 收稿日期:2018-03-11 出版日期:2018-08-08 发布日期:2014-06-28
  • 通讯作者: 杨丙成,E-mail:bcyang@ecust.edu.cn
  • 基金资助:

    国家自然科学基金项目（21477037）.

Fabrication of conventional ion chromatography-capacitively coupled contactless conductivity detector

CHEN Xiaohua1, HOU Yanjie1, YANG Bingcheng1, AI Lei2   

  1. 1. School of Pharmacy East China University of Science and Technology, Shanghai 200237, China;
    2. Suzhou Minghao Chromatographic Corperation, Suzhou 215500, China
  • Received:2018-03-11 Online:2018-08-08 Published:2014-06-28
  • Supported by:

    National Natural Science Foundation of China (No.21477037).

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摘要：

通过考察电极长度及电极间距、检测管管径及材质、激励信号频率、电压和波形等参数对信噪比的影响，研制了一种适用于常规型离子色谱系统的电容耦合非接触式电导检测器（C4D）。在抑制模式下，该检测器对常见无机阴离子（F-、Cl-、NO2-、Br-、NO3-和SO42-）的检出限（信噪比=3）为0.02~0.08 μmol/L；峰面积的相对标准偏差<1.8%（n=6）；在0.1~10 μmol/L范围内上述6种无机阴离子线性关系良好，相关系数（R2）>0.999。自制C4D的主要性能参数与商品化接触式电导检测器相当。该检测器具有结构简单、成本低廉、无电极污染等优点，有利于拓展离子色谱的应用范围。

关键词: 电容耦合非接触式电导检测器, 离子色谱, 信噪比, 阴离子

Abstract:

A conventional ion chromatography-capacitively coupled contactless conductivity detector (IC-C4D) was fabricated. The main parameters, such as the electrode length and gap, tube material and inner diameter, excitation frequency, voltage and waveforms, were optimized. The self-made C4D showed comparable performance to that of a commercial contact conductivity detector. Under the suppressed mode, the limits of detection of common inorganic anions (F-, Cl-, NO2-, Br-, NO3-, and SO42-) were 0.02-0.08 μmol/L. The relative standard deviations (RSDs) for the peak area were less than 1.8% (n=6). The linearities of the six common inorganic anions were achieved in the range of 0.1-10 μmol/L with correlation coefficients (R2)>0.9950. The advantages of such a C4D in a relatively conventional mode include simple structure, low fabrication cost and no electrode fouling, and it will help extend the application of IC.

Key words: anions, capacitively coupled contactless conductivity detector (C4D), ion chromatography (IC), signal-to-noise ratio (SNR)

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