International Journal For Multidisciplinary Research

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A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 6 Issue 3 May-June 2024 Submit your research before last 3 days of June to publish your research paper in the issue of May-June.

Risk Associated with Antibiotic in Irritable Bowel Syndrome (IBS), Role of Microbiota and Future Aspects

Author(s) Tonushyam Sonowal, Chinmoyee Deori, Leena Hujuri, Daisy Narzari, Dr. Jesim Ali Ahmed
Country India
Abstract Irritable bowel syndrome (IBS) is functional gastrointestinal (GI) disorder that characterized by abdominal pain in relation to disturbed bowel habits. It is a substantial burden on both patient health –related quality of life and healthcare cost. Although various path physiologic mechanisms have been formulated including visceral hypersensitivity, altered bowel motility, gut- brain dysregulations but it is believed that gut microbiome plays an important role in the genesis of symptoms. The composition and diversity of the gut micro biota can be modified by use of antibiotics, as they have the capacity to diminish the levels of advantageous bacteria while allowing the proliferation of detrimental bacteria. It is well known that micro biome takes a crucial role in development of IBS, but antibiotics itself is a potential risk factors for IBS has not been clarified yet. However, lack of highly predictive diagnostics biomarkers and the complexity and the heterogeneity of IBS patients make management difficult and unsatisfactory in most of the cases, thereby reducing patient health- related quality of life and increasing the sanitary burden. So, this review would help us to understand the risk factors associated with antibiotics in developing IBS, the role of gut micro biome and the other potential future approaches which are useful for the diagnosis, prevention and treatment of irritable bowel syndrome.
Keywords Irritable bowel syndrome (IBS), Gut microbiota, Antibiotic risk
Field Medical / Pharmacy
Published In Volume 6, Issue 1, January-February 2024
Published On 2024-02-23
Cite This Risk Associated with Antibiotic in Irritable Bowel Syndrome (IBS), Role of Microbiota and Future Aspects - Tonushyam Sonowal, Chinmoyee Deori, Leena Hujuri, Daisy Narzari, Dr. Jesim Ali Ahmed - IJFMR Volume 6, Issue 1, January-February 2024. DOI 10.36948/ijfmr.2024.v06i01.13916
DOI https://doi.org/10.36948/ijfmr.2024.v06i01.13916
Short DOI https://doi.org/gtjtts

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