AccScience Publishing / MI / Volume 1 / Issue 1 / DOI: 10.36922/mi.2600
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CASE SERIES

Klebsiella pneumoniae-related rare multi-site infections: A case series

Shanshan Jin1† ,  Yu Zhang1† ,  Lina Zhao1 ,  Qiuping Huang1 ,  Hui Xie1 ,  Jian Lu1* ,  Ruilan Wang1,2*
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1 Department of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai 200080, China
2 Department of Critical Care Medicine, Shanghai General Hospital of Nanjing Medical University, Shanghai 200080, China
MI 2024, 1(1), 2600 https://doi.org/10.36922/mi.2600
Submitted: 31 December 2023 | Accepted: 27 February 2024 | Published: 27 March 2024
© 2024 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
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Abstract

The incidence of Klebsiella pneumoniae (KP)-related rare multi-site infections has been progressively rising in China, highlighting the need for heightened awareness of the devastating complications associated with metastatic infections caused by this bacterium. This article describes the cases of six adult patients diagnosed with KP-related multi-site infections at a tertiary hospital in China from 2020 to 2022. The cases report a detailed examination of clinical features, laboratory test findings, bacterial culture results, imaging examinations, treatments administered, and subsequent outcomes. Notably, metastatic infections developed in four patients with uncontrolled diabetes. Despite strict glycemic control and timely antibiotic administration in three patients, their conditions deteriorated rapidly. The unfavorable prognosis in these patients may be attributed to delayed medical intervention, inadequate diabetes control, and unattended abscesses. The findings of this case series underscore the importance of glycemic control, percutaneous abscess drainage, and appropriate antibiotic selection in managing KP infections. Attaining early diagnosis and treatment of KP-related multi-site infections could potentially enhance patient outcomes.

Keywords
Klebsiella pneumoniae
Meningitis
Liver abscess
Metastatic infections
Case report
Funding
This study was supported by the Shen Kang Hospital Development Center Project for Technical Standardization Management and Promotion (Grant no. SHDC22023239), and the Shanghai Hospital Development Center Foundation (Grant no. SHDC22022206).
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Conflict of interest
The authors declare no conflicts of interest.
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Microbes & Immunity, Electronic ISSN: 3029-2883 Published by AccScience Publishing
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