Design of Pectin-Based Hydrogel Microspheres for Targeted Pulmonary Delivery
Abstract
:1. Introduction
2. Results and Discussion
2.1. Hydrogel Microsphere Production Process Optimization
2.2. Effects of Gelatin Concentration and Solvent on Hydrogel Microsphere Coatings
2.3. Morphology, Surface Properties, and Chemistry of Microspheres
2.4. Responsiveness of Hydrogel Microspheres
3. Conclusions
4. Materials and Methods
4.1. Materials
4.2. Pectin-Based Hydrogel Microsphere Production
4.3. Optimization of the Hydrogel Microsphere Production Process
4.4. Gelatin Coating of Microspheres
4.5. Characterization of Microspheres
4.6. Responsiveness of Hydrogel Microspheres in Simulated Lung Fluid
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Chai, A.; Schmidt, K.; Brewster, G.; Xiong, L.S.P.; Church, B.; Wahl, T.; Sadabadi, H.; Kumpaty, S.; Zhang, W. Design of Pectin-Based Hydrogel Microspheres for Targeted Pulmonary Delivery. Gels 2023, 9, 707. https://doi.org/10.3390/gels9090707
Chai A, Schmidt K, Brewster G, Xiong LSP, Church B, Wahl T, Sadabadi H, Kumpaty S, Zhang W. Design of Pectin-Based Hydrogel Microspheres for Targeted Pulmonary Delivery. Gels. 2023; 9(9):707. https://doi.org/10.3390/gels9090707
Chicago/Turabian StyleChai, Andy, Keagan Schmidt, Gregory Brewster, Lu Shi Peng Xiong, Benjamin Church, Timothy Wahl, Hamed Sadabadi, Subha Kumpaty, and Wujie Zhang. 2023. "Design of Pectin-Based Hydrogel Microspheres for Targeted Pulmonary Delivery" Gels 9, no. 9: 707. https://doi.org/10.3390/gels9090707