J Korean Med Sci. 1999 Aug;14(4):448-450. English.
Published online Jun 19, 2009.
https://doi.org/10.3346/jkms.1999.14.4.448
Published online Jun 19, 2009.
https://doi.org/10.3346/jkms.1999.14.4.448
Copyright © 1999 The Korean Academy of Medical Sciences
Case Report
Myelodysplastic syndrome that progressed to acute myelomonocytic leukemia with eosinophilia showing peculiar chromosomal abnormality: a case report
Seong Ho Kim,
Cheol Won Suh,
Seong Jun Choi,
Jung Gyun Kim,
Je Hwan Lee,
Sung Bae Kim,
Sang We Kim,
Kyoo Hyung Lee,
Jung Shin Lee,
Woo Kun Kim,
Sang Hee Kim,
Eul Ju Seo
and Hyun Sook Chi
Abstract
Myelodysplastic syndrome is a closely related group of acquired bone marrow disorders characterized by ineffective and dysplastic hematopoiesis. These clonal disorders frequently progress to acute leukemia. Acute myelomonocytic leukemia with eosinophilia is characterized by an increase in abnormal eosinophils in the bone marrow, relatively good clinical course and inv (16) chromosomal abnormality. We experienced one case of refractory anemia with excess blasts which progressed to refractory anemia with excess blasts in transformation and finally to acute myelomonocytic leukemia with eosinophilia showing peculiar chromosomal abnormalities of der (1;7).
Keywords
Myelodysplastic syndromes; Leukemia, myelomonocytic, acute; Eosinophilia; Chromosome abnormalities
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