| Use of Spectral-Domain Optical Coherence Tomography to Analyze Macular Thickness According to Refractive Error. |
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Seung Hoon Kim, Joo Youn Park, Tae Kwann Park, Young Hoon Ohn |
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Department of Ophthalmology, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea. yhohn@schmc.ac.kr |
| 스펙트럼 영역 빛간섭단층촬영기를 이용한 근시 정도에 따른 황반 구조의 정량적 분석 |
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김승훈⋅박주연⋅박태관⋅온영훈 |
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Department of Ophthalmology, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea |
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| Abstract |
PURPOSE
To investigate the correlation of macular retinal thickness and refractive error using spectral-domain optical coherence tomography (SD-OCT). METHODS: A total of 120 eyes with no posterior abnormalities were enrolled in the present study. Subjects were divided into 3 groups based on their spherical equivalent. Visual acuity, refraction, slit lamp examination, tonometry and fundus examination were performed. Retinal thickness between the RPE and IS/OS junction was measured at the fovea, 1 mm (inner ring) and 2 mm (outer ring) superiorly, inferiorly, nasally and temporally using SD-OCT. Overall average thickness, average foveal thickness, and the inner and outer ring macular thickness were measured. RESULTS: The average foveal thickness was significantly greater in the high myopic eyes than in the low to moderate myopic and emmetropic eyes (p = 0.001). However, the RPE-IS/OS junction thickness of the foveola and the outer macular thickness were significantly lower (p = 0.001, p = 0.002) in the high myopic eyes. There was a weak, but significant negative correlation between refractive error and average foveal thickness (r = -0.38, p = 0.001). A positive correlation was found between refractive error and the RPE-IS/OS junction thickness (r = 0.40, p = 0.001). CONCLUSIONS: Macular retinal thickness is related to refractive error in normal subjects. Effects of eyeball elongation are more apparent in high myopic eyes than in low to moderate myopic eyes. A significant decline in the RPE-IS/OS junction thickness suggests the photoreceptor outer segments in the foveola are damaged in high myopic eyes. |
| Key Words:
Macula;Macular thickness;Myopia;Refractive error;Spectral-domain optical coherence tomography |
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