Induction of Total-body Hyperthermia by Means of Whole-abdominal Hyperthermia Using the Radiofrequency Capacitive Hyperthermia System

Ryuichi Hamazoe; Shigemasa Koga; Michio Maeta; Norio Shimizu; Atsunobu Murakami; Toshiro Wakatsuki; Yasuhiro Inoue; Minoru Ishiguro; Takashi Sawata; Tetsu Shimizu

doi:10.3191/thermalmedicine.4.273

Ryuichi Hamazoe, Shigemasa Koga, Michio Maeta, Norio Shimizu, Atsunobu Murakami, Toshiro Wakatsuki, Yasuhiro Inoue, Minoru Ishiguro, Takashi Sawata, Tetsu Shimizu

Author information

Ryuichi Hamazoe
First Department of Surgery, Tottori University School of Medicine
Shigemasa Koga
First Department of Surgery, Tottori University School of Medicine
Michio Maeta
First Department of Surgery, Tottori University School of Medicine
Norio Shimizu
First Department of Surgery, Tottori University School of Medicine
Atsunobu Murakami
First Department of Surgery, Tottori University School of Medicine
Toshiro Wakatsuki
First Department of Surgery, Tottori University School of Medicine
Yasuhiro Inoue
First Department of Surgery, Tottori University School of Medicine
Minoru Ishiguro
First Department of Surgery, Tottori University School of Medicine
Takashi Sawata
First Department of Surgery, Tottori University School of Medicine
Tetsu Shimizu
First Department of Surgery, Tottori University School of Medicine

Keywords: radiofrequency capacitive hyperthermia, whole-abdominal hyperthermia, total-body hyperthermia, total-body hyperthermia with RF heating

JOURNAL FREE ACCESS

1988 Volume 4 Issue 4 Pages 273-278

DOI https://doi.org/10.3191/thermalmedicine.4.273

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Abstract

The adult mongrel dogs were divided into 2 groups of 8 each infused and not infused physiological saline intraperitoneally. The whole abdomen was heated with 8 MHz radiofrequency capacitive hyperthermia system. The mean increase in total-body temperature under the whole-abdominal hyperthermia was 6.4°C for the saline-infused group and 5.1°C for the non-infused group. The total-body temperature reached 40°C about 50 min after the start of heating in 4 of 5 animals of the saline infused group ; in 3 of the 4 animals died, in which the highest temperature of the peritoneum in the deep abdomen or liver exceeded 43.5°C. The permissible range in heating the visceral organs seemed to be less than 43.5°C in due consideration of the effects of heat on the visceral organs. Changes in the liver were very marked in blood biochemical data and microscopical examination of the visceral organs. It was probable to achieve mild-high total-body temperature about 40°C by means of whole-abdominal hyperthermia within 43.5°C for the permissible temperature of the visceral organs.

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