Combined treatment with local hyperthermia, radiation and chemotherapy was performed for a young female with a retrovesical tumor histologically diagnosed as an undifferentiated mesenchymal tumor.
The patient was 17 years old and had suffered from left flank pain since October 1991. Computed tomography and magnetic resonance imaging revealed a large retrovesical tumor. She was operated in December 1991, but the tumor was not resected completely due to adhesion to the pelvis. After the operation, she received intra-arterial infusion of cisplation, doxorubicin, and mitomycin C, and thereafter received Lineac irradiation to a total dose of 50.4 grays. Hyperthermia of the pelvis was conducted from March 1991 to December 1993 for 26 sessions as an outpatient using a Thermotron RF-8.
The tumor decreased markedly in size after this combination of hyperthermia, chemotherapy, and radiation. The patient is currently well and is receiving hyperthermia, chemotherapy, and radiation. The patient is currently well and is receiving hyperthermia once a month.
This case indicates that combined local hyperthermia, chemotherapy, and radiation is useful for the treatment of retrovesical tumors.