Email this article NEW PLANT SPECIES SHOWING ANTIPROTOZOIAN ACTIVITY
- Authors: Osipov A.V.1, Starkov V.G.1, Trang N.T.2, Khoa N.C.3, Anh H.N.3, Dung L.T.3, Tsetlin V.I.1, Utkin Y.N.1, Cheremnykh E.G.4
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Affiliations:
- Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
- Nguyen Tat Thanh University
- Institute of Applied Materials Science, Vietnam Academy of Science and Technology
- Mental Health Research Centre
- Issue: Vol 508, No 1 (2023)
- Pages: 84-90
- Section: Articles
- URL: https://journals.rcsi.science/2686-7389/article/view/135683
- DOI: https://doi.org/10.31857/S2686738922600650
- EDN: https://elibrary.ru/MOCGXJ
- ID: 135683
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Abstract
The effects of extracts of ten plant species growing in Russia and five species growing in Vietnam on the growth and survival of ciliates Tetrahymena pyriformis were studied. T. pyriformis is from the Protozoa subkingdom, which also includes pathogens of protozoan infections. Extraction of dried plants was carried out with acidic and alkaline aqueous solutions, as well as with an aqueous ethanol solution. Various amounts of extracts were added to the infusoria cells and the number of survived cells was recorded after 1 and 24 hours. We found that our samples of several plants, including wormwood, harmala, and licorice, similarly to those studied earlier, have antiprotozoal activity, which may indicate a sameness of secondary metabolites in plants from different regions. Using the ciliate T. pyriformis as a model organism, the presence of antiprotozoal activity in extracts of lilac, chondrilla, cinquefoil, hop and elm was shown for the first time.
Keywords
About the authors
A. V. Osipov
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: utkin@ibch.ru
Russian Federation, Moscow
V. G. Starkov
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: utkin@ibch.ru
Russian Federation, Moscow
Nguyen Thi Thuy Trang
Nguyen Tat Thanh University
Email: utkin@ibch.ru
Vietnam, Ho Chi Minh City
Nguyen Cuu Khoa
Institute of Applied Materials Science, Vietnam Academy of Science and Technology
Email: utkin@ibch.ru
Vietnam, Ho Chi Minh City
Hoang Ngoc Anh
Institute of Applied Materials Science, Vietnam Academy of Science and Technology
Email: utkin@ibch.ru
Vietnam, Ho Chi Minh City
Le Tien Dung
Institute of Applied Materials Science, Vietnam Academy of Science and Technology
Email: utkin@ibch.ru
Vietnam, Ho Chi Minh City
V. I. Tsetlin
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: utkin@ibch.ru
Russian Federation, Moscow
Yu. N. Utkin
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Author for correspondence.
Email: utkin@ibch.ru
Russian Federation, Moscow
E. G. Cheremnykh
Mental Health Research Centre
Email: utkin@ibch.ru
Russian Federation, Moscow
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