Hydrogels Based on Interpolymer Complexes of Sodium Alginate and Synthetic Polyacids

I. F. Volkova; Волкова И. Ф.; E. S. Grigoryan; Григорян Э. С.; G. A. Shandryuk; Шандрюк Г. А.; M. Yu.  Gorshkova; Горшкова М. Ю.

doi:10.31857/S230811202370030X

Hydrogels Based on Interpolymer Complexes of Sodium Alginate and Synthetic Polyacids

Authors: Volkova I.F.¹, Grigoryan E.S.¹, Shandryuk G.A.¹, Gorshkova M.Y.¹
Affiliations:
1. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences
Issue: Vol 65, No 1 (2023)
Pages: 54-64
Section: ПОЛИМЕРНЫЕ ГЕЛИ
URL: https://journals.rcsi.science/2308-1120/article/view/135338
DOI: https://doi.org/10.31857/S230811202370030X
EDN: https://elibrary.ru/UYYESQ
ID: 135338

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Abstract
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Abstract

Effect of the structure of synthetic polyacids on the formation and properties of their interpolymer complexes with sodium alginate is investigated. The hydrogels was shown to be predominantly formed via hydrogen bonds, with their type depending on the structure of polyacid and the amount of bound water. Study of the behavior of the hydrogels in water and phosphate-buffed saline with рН 7.2 demonstrates that the properties of the hydrogels are influenced by the ratio of components and the treatment temperature, in addition to the nature of polyacid. The possibility of using hydrogels as a basis for drug delivery systems is examined by the example of preparation lidocaine.

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