Email this article Application of the Knorr reaction for the directional synthesis of pyrazole derivative as a biologically active co-ligandes of gold glyco-nanoparticles
- Authors: Ershov A.Y.1, Martynenkov A.A.1, Lagoda I.V.2, Batyrenko A.A.2
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Affiliations:
- Institute of Macromolecular Compounds of Russian Academy of Sciences
- State Research Testing Institute of Military Medicine, Ministry of Defense of the Russian Federation
- Issue: Vol 59, No 11 (2023)
- Pages: 1489-1491
- Section: Articles
- URL: https://journals.rcsi.science/0514-7492/article/view/247263
- DOI: https://doi.org/10.31857/S0514749223110101
- EDN: https://elibrary.ru/NCKVEC
- ID: 247263
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Abstract
Based on the reaction of acetylacetone with 6-mercaptohexanoic and 11-mercaptoundecanoic acid hydrazides, a method was developed for the synthesis of previously unknown 1-(ω-mercaptoacyl)-3,5-dimethylpyrazole as promising сo-ligand for the preparation of gold glyco-nanoparticles for biomedical purposes.
Keywords
About the authors
A. Y. Ershov
Institute of Macromolecular Compounds of Russian Academy of Sciences
Email: ershov305@mail.ru
A. A. Martynenkov
Institute of Macromolecular Compounds of Russian Academy of Sciences
I. V. Lagoda
State Research Testing Institute of Military Medicine, Ministry of Defense of the Russian Federation
A. A. Batyrenko
State Research Testing Institute of Military Medicine, Ministry of Defense of the Russian Federation
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