Piperacillin-tazobactam induced thrombocytopenia: A case report

Nikhil M Sunny 1, *, Neha Susan Vinu 1 and. S. K Mathew 2

1 Pharm. D Intern, Nazareth College of Pharmacy, Othera , Thiruvalla, Kerala, India.
2 Department of General Medicine, Believers Church Medical College Hospital, Thiruvalla, India.
 
Research Article
International Journal of Science and Research Archive, 2023, 09(02), 739–741.
Article DOI: 10.30574/ijsra.2023.9.2.0628
Publication history: 
Received on 23 June 2023; revised on 10 August 2021; accepted on 13 August 2023
 
Abstract: 
Piperacillin-tazobactam is a commonly used antibiotic that belongs to penicillin and beta-lactam inhibitors, which has a wide range of gram-negative bacteria and limited gram-positive activity. This case report presents one of the rare ADR of piperacillin–tazobactam –thrombocytopenia where a dramatic improvement within 24hrs in platelet count was observed after withdrawing the drug. Few cases of piperacillin tazobactam-induced thrombocytopenia have been reported. 
 
Keywords: 
Piperacillin-tazobactam; Thrombocytopenia; Multi-drug-resistant; Adverse Drug Reaction
 
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