Gold Nanoparticles as anti-ovarian cancer therapy

Abstract

Cancer of the ovary is one of the most common types of women cancer in the world. In Iraq, it is seventh cancer in Iraqi women. Nanomedicine emerged as a possible alternative for cancer therapy. Many nanoparticles have been tested on different cancer cell lines with promising results. Gold nanoparticles (AuNPs) showed interesting biocompatibility properties such as selective accumulation in tumor cells. The currentwork was aimed to study cytotoxicity and cell death induced by AuNPson ovarian cancer cells. Methods: Cytotoxicity of AuNPs was assessed by MTT viability assay. Results: AuNPs nanoparticles from 25 up to 100 µg/mL for 72 hours exerted concentration-dependent cytotoxicity. Conclusion: Gold nanoparticles induce cytotoxicity in ovarian cancer cells and Induce cell death and considered promising as cancer therapy.