Determination of Anti-Inflammatory Activity of Coumarin Compounds of Coldenia Procumbens Linn

S. Babu¹ , V. Ambikapathy² , A. Panneerselvam³

1. Department of Botany & Microbiology, A.V.V.M. Sri Pushpam College, Poondi Thanjavur, India.
2. Department of Botany & Microbiology, A.V.V.M. Sri Pushpam College, Poondi Thanjavur, India.
3. Department of Botany & Microbiology, A.V.V.M. Sri Pushpam College, Poondi Thanjavur, India.

Section:Research Paper, Product Type: Isroset-Journal
Vol.5 , Issue.5 , pp.77-79, Oct-2018

CrossRef-DOI:   https://doi.org/10.26438/ijsrbs/v5i5.7779

Online published on Oct 31, 2018

Copyright © S. Babu, V. Ambikapathy, A. Panneerselvam . This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
 

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Abstract :
In the present study, invitro anti-inflammatory activity was tested using coumarin compound of C.procumbens. Coumarins are a group of polyphenolic compounds isolated by TLC method from C.procumbens plant extract. In anti-inflammation study, the methanolic extract showed high percentage of inhibition observed in egg albumin denaturation studies was 78.8% of 0.8µg/ml concentration of coumarin compounds where as compared to standard drug Diclofenac sodium 74.8%. While, bovine serum albumin denaturation assay was 67.8 % of 0.8 µg/ml concentration when compared to other concentration of coumarin compounds. The results were discussed.

Key-Words / Index Term :
C.procumbens, coumarin, BSA, Egg albumin

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