Comment on ‘Multilayered Stable 2D Nano-Sheets of Ti2NTx MXene: Synthesis, Characterization, and Anticancer Activity’

A recent article entitled “Multilayered stable 2D nano-sheets of Ti₂NT_x MXene: synthesis, characterization, and anticancer activity” published in this journal, claimed that two-dimensional Ti₂NT_x MXene could be synthesized by selectively etching Ti₂AlN in concentrated hydrofluoric acid at room temperature. However, the X-ray diffraction pattern of Ti₂NT_x MXene reported in that paper is completely different with those of other MXenes. In this comment, it is argued that the samples synthesized in that paper were NOT Ti₂NT_x MXene at all. Although carbide MXenes can be made by selectively etching A layers from MAX phase, it is very difficult or impossible to make nitride MXenes (Ti₂NT_x) by the same way.