Elter, Adrian ; Bogen, Jan P. ; Habermann, Jan ; Kolmar, Harald (2024)
Vom Huhn abgeleitete Antikörper für Diagnostik und Immuntherapie.
In: BIOspektrum : Das Magazin für Biowissenschaften, 2021, 27 (5)
doi: 10.26083/tuprints-00023545
Article, Secondary publication, Publisher's Version
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| Item Type: | Article |
|---|---|
| Type of entry: | Secondary publication |
| Title: | Vom Huhn abgeleitete Antikörper für Diagnostik und Immuntherapie |
| Language: | German |
| Date: | 30 April 2024 |
| Place of Publication: | Darmstadt |
| Year of primary publication: | September 2021 |
| Place of primary publication: | Berlin ; Heidelberg |
| Publisher: | Springer |
| Journal or Publication Title: | BIOspektrum : Das Magazin für Biowissenschaften |
| Volume of the journal: | 27 |
| Issue Number: | 5 |
| DOI: | 10.26083/tuprints-00023545 |
| Corresponding Links: | |
| Origin: | Secondary publication DeepGreen |
| Abstract: | Due to the large evolutionary distance between birds (Aves) und humans, immunization of chickens with human proteins results in a strong response of the bird’s adaptive immune system to proteins of mammalian origin. Additionally, chicken-derived antibodies display less undesired cross-reactivity in analytical setups than conventional rodent-derived antibodies. Due to these features as well as the facile amplification of antibody-coding genes, chicken-derived antibodies emerged as promising molecules for the immunotherapy and various biotechnological applications. |
| Uncontrolled Keywords: | Life Sciences, general, Biochemistry, general, Human Genetics, Microbiology, Pharmacology/Toxicology |
| Status: | Publisher's Version |
| URN: | urn:nbn:de:tuda-tuprints-235454 |
| Classification DDC: | 500 Science and mathematics > 540 Chemistry 500 Science and mathematics > 570 Life sciences, biology 600 Technology, medicine, applied sciences > 610 Medicine and health |
| Divisions: | 07 Department of Chemistry > Clemens-Schöpf-Institut > Fachgebiet Biochemie |
| Date Deposited: | 30 Apr 2024 09:10 |
| Last Modified: | 30 Apr 2024 09:11 |
| SWORD Depositor: | Deep Green |
| URI: | https://tuprints.ulb.tu-darmstadt.de/id/eprint/23545 |
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