Research Article
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Year 2024, Volume: 12 Issue: 1, 26 - 39, 02.05.2024
https://doi.org/10.24998/maeusabed.1464209

Abstract

Project Number

0566-DR-19

References

  • Abdelrazek, H.M.A., Ismail, T.A., El-Azzazi, F.E., Elsayed, D.H., 2018. Hematological and Metabolic Alterations in Egyptian Buffaloes During Transition Period. Egyptian Academic Journal of Biological Sciences 10(1), 69- 78. https://doi.org/10.21608/EAJBSC.2018.13657.
  • Altıner, A., Şahin, I., Bilal, T., Vural, H., 2016. Kan Leptin, Grelin ve Adiponektin Düzeylerini Etkileyen Faktörler. Turkiye Klinikleri Journal of Veterinary Sciences 7(1), 15-23. https://doi.org/10.5336/vetsci.2016-51738.
  • Andersen, J.B., Madsen, T.G., Larsen, T., Ingvartsen, K.L., Nielsen, M.O., 2005. The Effects of Dry Period Versus Continuous Lactation on Metabolic Status and Performance in Periparturient Cows. Journal of Dairy Science 88, 3530–3541. https://doi.org/10.3168/jds.S0022-0302(05)73038-1
  • Arslan, M.Ö., Sarı, B., Kara, M., Taşçı, G.T., Ekinci, A.İ., Gündüz, N., 2012. Kars Yöresinde Periparturient Dönemdeki İneklerde Eimeria ve Cryptosporidium Türlerinin Yaygınlığı Üzerine Araştırmalar. Kafkas Üniversitesi Veteriner Fakültesi Dergisi 18, 65-70. https://doi.org/10.9775/kvfd.2011.599.
  • Aslan, V., Eren, Ü., Sevinç, M., Öztok, İ., Işık, K., 1993. Yüksek Süt Verimli İneklerde Kuru Dönem ve Doğum Sonrası Metabolik Profildeki Degişiklikler ve Bunların Karaciğer Yağlanması ile İlgisi. Selçuk Üniversitesi Veteriner Fakültesi Dergisi 9(2), 38-45.
  • Bell, A.W., Bauman, D.E., 1997. Adaptations of Glucose Metabolism During Pregnancy and Lactation. Journal of Mammary Gland Biology and Neoplasia 2(3) 265-78. https://doi.org/10.1023/a:1026336505343
  • Benazzouz, H., Benlatreche, C., 2016. Blood biochemical parameters in Ouled Djellal ewes in the periparturient period. Der Pharma Chemica 8(18), 406-410.
  • Bhoite, S., Khodke, M., Dalvi, S., Golher, D., 2019. Protein Profile During Peripartum Period in Berari Goat. Chemical Science Review and Letters 8(29), 48-52.
  • Block, S.S., Butler, W.R., Ehrhardt, R.A., Bell, A.W., Amburgh, M.E.V, Boisclair, Y.R., (2001). Decreased concentration of plasma leptin in periparturient dairy cows is caused by negative energy balance. International Journal of Endocrinology 171, 339–348. https://doi.org/10.1677/joe.0.1710339
  • Bradford, B.J., Allen, M.S., 2008. Negative energy balance increases periprandial ghrelin and growth hormone concentrations in lactating dairy cows. Domestic Animal Endocrinology 34(2), 196-203. https://doi.org/10.1016/j.domaniend.2007.02.002
  • Boudebza, A., Arzour-Lakhel, N., Abdeldjelil, M.C., Dib, A.L., Lakhdara, N., Benazzouz, H., Benlatreche, C., 2016. Blood biochemical parameters in Ouled Djellal ewes in the periparturient period. Der Pharma Chemica 8(18), 406-410.
  • Celi, P., Trana, A.D., Quaranta, A., 2008. Metabolic profile and oxidative status in goats during the peripartum period. Australian Journal of Experimental Agriculture 48, 1004-1008. https://doi.org/10.1071/EA07410
  • Chalmeh, A., Pourjafar, M., Badiei, K., Mirzaei, A., Mazrouei, S.M., Saadat, A.I., Zarei, M.H., 2017. Circulating metabolic biomarkers and hormones and their relationships at different pre- and post-parturition periods of Ghezel ewes. Iranian Journal of Ruminants Health Research 2(2), 1-22. https://doi.org/10.22055/ijrhr.2019.23724.1013
  • Contreras, G.A., Strieder-Barboza, C., Raphae, W., 2017. Adipose tissue lipolysis and remodeling during the transition period of dairy cows. Journal of Animal Science and Biotechnology 8(41), 1-12. https://doi.org/10.1186/s40104-017-0174-4
  • Djoković, R., Kurćubić, V., Ilić, Z., Cincović, M., Petrović, M., Fratrić, N., Jašović, B., 2013. Evaluation of metabolic status in Simmental dairy cows during late valuation of metabolic status in Simmental dairy cows during late pregnancy and early lactation. Veterinarski Arhiv 83(6), 593-602.
  • Elshahawy, I.I., Abdullaziz, I.A., 2017. Hemato-Biochemical Profiling in Relation to Metabolic Disorders in Transition Dairy Cows. Alexandria Journal of Veterinary Sciences 55 (2), 25-33. https://doi.org/10.5455/ajvs.275430
  • Enriori, P.J., Evans, A.E., Sinnayah, P., Cowley, M.A., 2006. Leptin Resistance and Obesity. Obesity., 5, 254-258. https://doi.org/10.1038/oby.2006.319
  • Eşki, F., Taşal, İ., Karslı, M.A., Şendağ, S., Uslu, BA., Wagner, H., Wehrend, A., 2015. Concentrations of NEFA, β-HBA, triglycerides, and certain blood metabolites in healthy colored Angora goats during the peripartum period. Turkish Journal of Veterinary & Animal Sciences 39, 401-405. https://doi.org/10.3906/vet-1412-25
  • Fleming-Waddell, J.N., Keisler, D.H., Jackson, S.P., Blanton, J.R., 2007. Characterization of Leptin Levels in Gestating Callipyge Ewes. Asian-Australasian Journal of Animal Sciences 20(1), 41-44. https://doi.org/10.5713/ajas.2007.41
  • Giuliotti, L., Lai, O., Cavallina, R., Alfieri, L., Rabusca, G., Benvenuti, M.N., 2014. Changes in physiological and immunological parameters during the peripartum period in Zerasca sheep. Polish Journal of Veterinary Sciences 17(4), 737–739. https://doi.org/10.2478/pjvs-2014-0109
  • Janků, L., Pavlata, L., Mišurová, L., Filípek, J., Pechová, A., Dvořák, R., 2011. Levels of protein fractions in blood serum of periparturient goats. Acta Vet. Brno 80, 185–190. https://doi.org/10.2754/avb201180020185
  • Jeong, J.K., Choi, I.S., Moon, S.H., Kang, H.G., Kim, I.H., 2008. Relationship between serum magnesium concentration during the transition period, peri and postpartum disorders, and reproductive performance in dairy cows. Journal of Livestock Science 213, 1-6. https://doi.org/10.1016/j.livsci.2018.04.013
  • Jin, L.N, Sun, H., Dan, S., Li, S, Zhang, C, Zhang, C, Ren, X, Shan, D, Ling, S., 2019. Serotonin regulates maternal calcium homeostasis during the perinatal period of sheep. Animal Science Journal 97(12), 5009–5015. https://doi.org/10.1093/jas/skz346
  • Jones, A.K., Gately, R.E., Kellog, T.D., Zinn, S.A., Govoni, K.E., Reed, S.A., 2018. Evaluation of the Nova Vet Meter for sheep-side monitoring of β-hydroxybutyric acid (BHBA) and description of ewe BHBA during late gestation in three flocks from the Northeastern U.S. Research in Veterinary Science 118, 491-497. https://doi.org/10.1016/j.rvsc.2018.05.002
  • Kabara, E., Sordillo, L.M., Holcombe, S., Contreras, G.A., 2014. Adiponectin links adipose tissue function and monocyte inflammatory responses during bovine metabolic stress. Comparative Immunology, Microbiology and Infectious Diseases 37, 49–58. https://doi.org/10.1016/j.cimid.2013.10.007
  • Karagiannis, I., Panousis, N., Kiossis, E., Tsakmakidis, I., Lafi, S., Arsenos, G., Boscos, C., Brozos, C., 2014. Associations of pre-lambing body condition score and serum -hydroxybutyric acid and non-esterified fatty acids concentrations with periparturient health of Chios dairy ewes. Small Ruminant Research 120(1), 164-173. https://doi.org/10.1016/j.smallrumres.2014.05.001.
  • Karapehlivan, M., Atakisi, E., Atakisi, O., Yucayurt, R., Pancarci, S.M., 2007. Blood biochemical parameters during the lactation and dry period in Tuj ewes. Small Ruminant Research 73, 267–271. https://doi.org/10.1016/j.smallrumres.2006.12.006
  • Kessler, E.C., Gross, J.J., Bruckmaier, R.M., Albrecht, C., 2014. Cholesterol metabolism, transport, and hepatic regulation in dairy cows during transition and early lactation. Journal of Dairy Science 97, 1–10. https://doi.org/10.3168/jds.2014-7926
  • Komatsu, T., Itoh, F., Sakumoto, R., Hodate, K., Obara, Y., Kushibiki, S., 2007. Changes in the gene expression of adiponectin and glucose transporter 12 (GLUT12) in lactating and non-lactating cows. Animal Science Journal 78, 98–102. https://doi.org/98-102 10.1111/j.1740-0929.2006. 00411.x
  • Kushibiki, S., 2011. Tumor necrosis factor-a-induced inflammatory responses in cattle. Animal Science Journal 82, 504–511. https://doi.org/10.1111/j.1740-0929.2011.00931.x
  • Küçükşen, D.U., 2017. Koyunlarda Doğum Sonrası Erken Laktasyon Döneminde Leptin ve Ghrelin Seviyelerin Değişimleri. . Atatürk Üniversitesi Veteriner Bilimleri Dergisi 12(3), 269-275. https://doi.org/10.17094/ataunivbd.299378
  • Laeger, T., Sauerwein, H., Tuchscherer, A., Bellmann, O., Metges, C.C., Kuhla, B., 2013. Concentrations of Hormones and Metabolites in Cerebrospinal Fluid and Plasma of Dairy Cows During the Periparturient Period. Journal of Dairy Science 96(5), 2883-93. https://doi.org/10.3168/jds.2012-5909
  • Lager, K., Jordan, E., 2012. The Metabolic Profile for the Modern Transition Dairy Cow. Mid-South Ruminant Nutrition Conference. Grapevine, Texas
  • Manat, T.D., Chaudhary, S.S., Singh, V.K., Patel, S.B., Puri, G. 2016. Hematobiochemical profile in Surti goats during post-partum period. Veterinary World 9, 19-24. https://doi.org/10.14202/vetworld.2016.19-24
  • Matarese, G., Moschos, S., Mantzoros, C.S., 2005. Leptin in Immunology. The Journal of Immunology 174 (6), 3137-3142. https://doi.org/10.4049/jimmunol.174.6.3137
  • Merhan, O., Özcan, A., 2010. Peripartum Dönemdeki Koyunlarda Seruloplazmin, Haptoglobin, Fibrinojen, Albümin ve Transferrin Düzeylerinin Araştırılması. Erciyes Üniversitesi Veteriner Fakültesi Dergisi 7(1), 13- 20.
  • Mohammadi, V., Anassori, E., Jafari, S., 2016. Measure of energy related biochemical metabolites changes during peri-partum period in Makouei breed sheep Veterinary Research Forum 7(1), 35 – 39.
  • Nazifi, S., Saeb, M., Ghavami, S.M., 2002. Serum lipid profile in Iranian fat-tailed sheep in late pregnancy, at parturition and during the post-parturition period. Journal of Research in Veterinary Medicine 49, 9-12. https://doi.org/10.1046/j.1439-0442.2002.00405.x
  • Nowroozi-Asl, A., Aarabi, N., Rowshan-Ghasrodashti, A., 2016. Ghrelin and its correlation with leptin, energy related metabolites and thyroidal hormones in dairy cows in transitional period. Polish Journal of Veterinary Sciences 19(1), 197–204. https://doi.org/10.1515/pjvs-2016-0024
  • Ohtani, Y., Takahashi, T., Sato, K., Ardiyanti, A., Song, SH, Sato, R., Onda, K., Wada, Y., Obara, Y., Suzuki, K., Hagino, A., Roh, S.G., Katoh, K., 2012. Changes in circulating adiponectin and metabolic hormone concentrations during periparturient and lactation periods in Holstein dairy cows. Animal Science Journal 83(12), 788-795. https://doi.org/10.1111/j.1740-0929.2012.01029.x
  • Peterson, A.B., Orth, M.W., Goff, J.P., Beede, D.K., 2005. Periparturient Responses of Multiparous Holstein Cows Fed Different Dietary Phosphorus Concentrations Prepartum. Journal of Dairy Science 88, 3582–3594. https://doi.org/10.3168/jds.S0022-0302(05)73043-5
  • Piccione, G., Caola, G., Giannetto, C., Grasso, F., Runzo, S.C., Zumbo, A., Pennisi, P., 2009. Selected biochemical serum parameters in ewes during pregnancy, post-parturition, lactation and dry period. Animal Science Papers and Reports 27(4), 321-330.
  • Piccione, G., Messina, V., Schembari, A., Casella, S., Giannetto, C., Alberghina, C., 2011. Pattern of serum protein fractions in dairy cows during different stages of gestation and lactation. Journal of Dairy Research 78 (4), 421-425. https://doi.org/10.1017/S0022029911000562
  • Popovic, V., 2006. Ghrelin. Current Opinion in Endocrinology 13, 70–75. https://doi.org/10.1097/01.med.0000200527.16276.e6
  • Proloa, P., Wonga, M., Licinioa, J., 1998. Leptin. The International Journal of Biochemistry & Cell Biology 30(12), 1285-1290. https://doi.org/10.1016/S1357-2725(98)00094-6
  • Rasmussen, A.N., Nielsen, M.O., Tauson, A.H., Blache, D., 2004. Leptin and lactogenesis in the periparturient dairy goat. Journal of Animal and Feed Sciences 13, 555−558. https://doi.org/10.22358/jafs/74034/2004
  • Rukkwamsuk, T., Wensing, T., Geelen, M.J.H., 1998. Effect of Overfeeding During the Dry Period on Regulation of Adipose Tissue Metabolism in Dairy Cows During the Periparturient Period. Journal of Dairy Science 81, 2904–2911. https://doi.org/10.3168/jds.S0022-0302(98)75851-5
  • Sadjadian, R., Seifi, H.A., Mohri, M., Naserian, A.A., Farzaneh, N., 2013. Variations of energy biochemical metabolites in periparturient dairy Saanen goats. Comparative Clinical Pathology 22, 449–456. https://doi.org/ 10.1007/s00580-012-1431-8
  • Schlegel, G., Ringseis, R., Keller, J., Schwarz, FJ., Eder, K., 2012. Changes in the expression of hepatic genes involved in cholesterol homeostasis in dairy cows in the transition period and at different stages of lactation. Journal of Dairy Science 95, 3826–3836. https://doi.org/10.3168/jds.2011-5221
  • Seifi, H.A., Dooz, M.G., Mohri, M., Naghadeh, B.D., Farzaneh, N., 2007. Variations of energy-related biochemical metabolites during transition period in dairy cows. Comparative Clinical Pathology 16, 253–258. https://doi.org/10.1007/s00580-007-0682-2
  • Sepúlveda-Varas, P., Huzzey, J.M., Weary, D.M., Keyserlingk, M.A.G., 2012. Behaviour, illness and management during the periparturient period in dairy cows. Animal Production Science 53(9), 988-999. https://doi.org/10.1071/AN12286
  • Sethi, J.K., Hotamisligil, G.S., 1999. The role of TNF alpha in adipocyte metabolism. Cell & Developmental Biology 10, 19-29. https://doi.org/10.1006/scdb.1998.0273
  • Sevinç, M., Başoğlu, A., Birdane, F., Gökçen, M., 1999. Sütçü Sığırlarda Kuru Dönem Doğum ve Doğum Sonrası Metabolik Profildeki Değişiklikler. Turkish Journal of Veterinary & Animal Sciences 3, 475-478.
  • Soares, G.S.L., Souto, R.J.T., Cajueiro, J.F.P., Afonso, J.A.B., Rego, R.O., Macêdo, A.T.M., Soares, P.C., Mendonça, C.L., 2018. Adaptive changes in blood biochemical profile of dairy goats during the period of transition. Revue de Medecine Veterinaire 169, 65-75.
  • Stojević, Z., Piršljin, J., Milinković-Tur, S., Zdelar-Tuk, M., Ljubić, B.B., 2005. Activities of AST, ALT and GGT in clinically healthy dairy cows during lactation and in the dry period. Veterinarski Arhiv., 75 (1), 67-73.
  • Temizel, E.M., Cihan, H., Levent, P., Sarıl, A., Özarda, Y., Yılmaz, Z., 2018. Comparison of pre- and postpartum serum leptin, ghrelin, and lipid levels in sheep. Turkish Journal of Veterinary & Animal Sciences 42, 177-183. https://doi.org/10.3906/vet-1705-87
  • Tharwat, M., Ali, A., Al-Sobayil, F., 2015. Hematological and biochemical profiles in goats during the transition period. Comparative Clinical Pathology 24, 1–7. https://doi.org/ 10.1007/s00580-013-1842-1
  • Trevisi, E., Amadori, M., Cogrossi, S., Razzuoli, E., Bertoni, G., 2012. Metabolic stress and inflammatory response in high-yielding, periparturient dairy cows. Res. Vet. Sci., 93, 695–704. https://doi.org/10.1016/j.rvsc.2011.11.008
  • Tunç, A.C., Birdane, F.M., Uyarlar, C., Yipel, F.A., Gültepe, E.E., Başer, D.F., Acar, A., 2017. Geçiş Dönemindeki Süt İneklerinde Damar İçi Novacoc® Uygulamasının Metabolik Profil Üzerine Etkileri. Kocatepe Veterinary Journal 10(4), 278-286. https://doi.org/10.5578/kvj.61911.
  • Turk, R., Podpecan, O., Mrkun, J., Kosec, M., Flegar-Mestric, Z., Perkov, S., Starice, J., Robic, M., Belic, M., Zrimsek, P., 2013. Lipid mobilisation and oxidative stress as metabolic adaptation processes in dairy heifers during transition period. Animal Reproduction Science 141, 109– 115. https://doi.org/10.1016/j.anireprosci.2013.07.014
  • Uyanık, F., Güvenç, K., Gültekin, M., Gürbulak, K., 2009. Koyunlarda Gebeliğin Değişik Dönemlerinde Leptin ve Progesteron Düzeyleri. Erciyes Üniversitesi Veteriner Fakültesi Dergisi 6(1), 31-36.
  • Vandehaar, M.J., Yousif, G., Sharma, B.K., Herdt, T.H., Emery, R.S., Allen, M.S., Liesman, J.S., 1999. Effect of Energy and Protein Density of Prepartum Diets on Fat and Protein Metabolism of Dairy Cattle in the Periparturient Period. Journal of Dairy Science 82, 1282–1295. https://doi.org/10.3168/jds.S0022-0302(99)75351-8
  • Vargová, M., Kováč, G., 2016. Periparturient Period in Terms of Body Condition Score and Selected Parameters of Hormonal Profiles. Folia Veterinaria., 60(1), 63-69. https://doi.org/ 10.1515/FV-2016-0010
  • Vostry, L., Milerski, M., Schmidova, J., Vostra-Vydrova, H., 2018. Genetic diversity and effect of inbreeding on litter size of the Romanov sheep. Small Ruminant Research 168, 25-31. https://doi.org/10.1016/j.smallrumres.2018.09.004
  • Yehia, S.G., Salem, N.Y., 2015. Assessment of Some Biochemical Parameters in Dairy Cows during Transition Period. International Journal of Veterinary Science 4(4), 227-230.

Investigation of Adiponectin, Leptin and Ghrelin Levels and Evaluation of Metabolic Profiles in the Periparturient Period in Romanov Sheep

Year 2024, Volume: 12 Issue: 1, 26 - 39, 02.05.2024
https://doi.org/10.24998/maeusabed.1464209

Abstract

The periparturient period is very important especially in terms of pregnancy-related herd-based diseases. In this period, especially for early diagnosis of subclinical diseases, a metabolic profile test is used. In the periparturient period, important changes occur in adipose tissue. Blood samples were collected from 16 Romanov sheep in the periparturient in serum tubes on the 21st, 14th, 7th, and postpartum days, and 7th, 14th, and 21st days after delivery. Metabolic profile and Adiponectin, Leptin and Ghrelin parameters evaluated from the blood samples. In the periparturient period, ELISA analyzes of TNF-α were performed for inflammatory evaluation. As a result of the analyzes, Prenatal increase in NEFA concentrations, postpartum decrease in cholesterol concentrations, postpartum increase and decrease in AST concentrations, postpartum increase in GGT concentrations, prenatal and postnatal increases in total protein concentrations, postpartum increase in BUN and creatinine concentrations, postpartum decrease in magnesium concentrations, Prenatal increase in adiponectin concentrations and postpartum decrease, postpartum decrease in leptin concentrations and prenatal increase in ghrelin concentrations occurred. With the results obtained, it was concluded that the evaluation of metabolic profile and adipose tissue is important in the diagnosis of diseases in the periparturient period.

Supporting Institution

Burdur Mehmet Akif Ersoy University Scientific Research Projects Coordinatorship

Project Number

0566-DR-19

References

  • Abdelrazek, H.M.A., Ismail, T.A., El-Azzazi, F.E., Elsayed, D.H., 2018. Hematological and Metabolic Alterations in Egyptian Buffaloes During Transition Period. Egyptian Academic Journal of Biological Sciences 10(1), 69- 78. https://doi.org/10.21608/EAJBSC.2018.13657.
  • Altıner, A., Şahin, I., Bilal, T., Vural, H., 2016. Kan Leptin, Grelin ve Adiponektin Düzeylerini Etkileyen Faktörler. Turkiye Klinikleri Journal of Veterinary Sciences 7(1), 15-23. https://doi.org/10.5336/vetsci.2016-51738.
  • Andersen, J.B., Madsen, T.G., Larsen, T., Ingvartsen, K.L., Nielsen, M.O., 2005. The Effects of Dry Period Versus Continuous Lactation on Metabolic Status and Performance in Periparturient Cows. Journal of Dairy Science 88, 3530–3541. https://doi.org/10.3168/jds.S0022-0302(05)73038-1
  • Arslan, M.Ö., Sarı, B., Kara, M., Taşçı, G.T., Ekinci, A.İ., Gündüz, N., 2012. Kars Yöresinde Periparturient Dönemdeki İneklerde Eimeria ve Cryptosporidium Türlerinin Yaygınlığı Üzerine Araştırmalar. Kafkas Üniversitesi Veteriner Fakültesi Dergisi 18, 65-70. https://doi.org/10.9775/kvfd.2011.599.
  • Aslan, V., Eren, Ü., Sevinç, M., Öztok, İ., Işık, K., 1993. Yüksek Süt Verimli İneklerde Kuru Dönem ve Doğum Sonrası Metabolik Profildeki Degişiklikler ve Bunların Karaciğer Yağlanması ile İlgisi. Selçuk Üniversitesi Veteriner Fakültesi Dergisi 9(2), 38-45.
  • Bell, A.W., Bauman, D.E., 1997. Adaptations of Glucose Metabolism During Pregnancy and Lactation. Journal of Mammary Gland Biology and Neoplasia 2(3) 265-78. https://doi.org/10.1023/a:1026336505343
  • Benazzouz, H., Benlatreche, C., 2016. Blood biochemical parameters in Ouled Djellal ewes in the periparturient period. Der Pharma Chemica 8(18), 406-410.
  • Bhoite, S., Khodke, M., Dalvi, S., Golher, D., 2019. Protein Profile During Peripartum Period in Berari Goat. Chemical Science Review and Letters 8(29), 48-52.
  • Block, S.S., Butler, W.R., Ehrhardt, R.A., Bell, A.W., Amburgh, M.E.V, Boisclair, Y.R., (2001). Decreased concentration of plasma leptin in periparturient dairy cows is caused by negative energy balance. International Journal of Endocrinology 171, 339–348. https://doi.org/10.1677/joe.0.1710339
  • Bradford, B.J., Allen, M.S., 2008. Negative energy balance increases periprandial ghrelin and growth hormone concentrations in lactating dairy cows. Domestic Animal Endocrinology 34(2), 196-203. https://doi.org/10.1016/j.domaniend.2007.02.002
  • Boudebza, A., Arzour-Lakhel, N., Abdeldjelil, M.C., Dib, A.L., Lakhdara, N., Benazzouz, H., Benlatreche, C., 2016. Blood biochemical parameters in Ouled Djellal ewes in the periparturient period. Der Pharma Chemica 8(18), 406-410.
  • Celi, P., Trana, A.D., Quaranta, A., 2008. Metabolic profile and oxidative status in goats during the peripartum period. Australian Journal of Experimental Agriculture 48, 1004-1008. https://doi.org/10.1071/EA07410
  • Chalmeh, A., Pourjafar, M., Badiei, K., Mirzaei, A., Mazrouei, S.M., Saadat, A.I., Zarei, M.H., 2017. Circulating metabolic biomarkers and hormones and their relationships at different pre- and post-parturition periods of Ghezel ewes. Iranian Journal of Ruminants Health Research 2(2), 1-22. https://doi.org/10.22055/ijrhr.2019.23724.1013
  • Contreras, G.A., Strieder-Barboza, C., Raphae, W., 2017. Adipose tissue lipolysis and remodeling during the transition period of dairy cows. Journal of Animal Science and Biotechnology 8(41), 1-12. https://doi.org/10.1186/s40104-017-0174-4
  • Djoković, R., Kurćubić, V., Ilić, Z., Cincović, M., Petrović, M., Fratrić, N., Jašović, B., 2013. Evaluation of metabolic status in Simmental dairy cows during late valuation of metabolic status in Simmental dairy cows during late pregnancy and early lactation. Veterinarski Arhiv 83(6), 593-602.
  • Elshahawy, I.I., Abdullaziz, I.A., 2017. Hemato-Biochemical Profiling in Relation to Metabolic Disorders in Transition Dairy Cows. Alexandria Journal of Veterinary Sciences 55 (2), 25-33. https://doi.org/10.5455/ajvs.275430
  • Enriori, P.J., Evans, A.E., Sinnayah, P., Cowley, M.A., 2006. Leptin Resistance and Obesity. Obesity., 5, 254-258. https://doi.org/10.1038/oby.2006.319
  • Eşki, F., Taşal, İ., Karslı, M.A., Şendağ, S., Uslu, BA., Wagner, H., Wehrend, A., 2015. Concentrations of NEFA, β-HBA, triglycerides, and certain blood metabolites in healthy colored Angora goats during the peripartum period. Turkish Journal of Veterinary & Animal Sciences 39, 401-405. https://doi.org/10.3906/vet-1412-25
  • Fleming-Waddell, J.N., Keisler, D.H., Jackson, S.P., Blanton, J.R., 2007. Characterization of Leptin Levels in Gestating Callipyge Ewes. Asian-Australasian Journal of Animal Sciences 20(1), 41-44. https://doi.org/10.5713/ajas.2007.41
  • Giuliotti, L., Lai, O., Cavallina, R., Alfieri, L., Rabusca, G., Benvenuti, M.N., 2014. Changes in physiological and immunological parameters during the peripartum period in Zerasca sheep. Polish Journal of Veterinary Sciences 17(4), 737–739. https://doi.org/10.2478/pjvs-2014-0109
  • Janků, L., Pavlata, L., Mišurová, L., Filípek, J., Pechová, A., Dvořák, R., 2011. Levels of protein fractions in blood serum of periparturient goats. Acta Vet. Brno 80, 185–190. https://doi.org/10.2754/avb201180020185
  • Jeong, J.K., Choi, I.S., Moon, S.H., Kang, H.G., Kim, I.H., 2008. Relationship between serum magnesium concentration during the transition period, peri and postpartum disorders, and reproductive performance in dairy cows. Journal of Livestock Science 213, 1-6. https://doi.org/10.1016/j.livsci.2018.04.013
  • Jin, L.N, Sun, H., Dan, S., Li, S, Zhang, C, Zhang, C, Ren, X, Shan, D, Ling, S., 2019. Serotonin regulates maternal calcium homeostasis during the perinatal period of sheep. Animal Science Journal 97(12), 5009–5015. https://doi.org/10.1093/jas/skz346
  • Jones, A.K., Gately, R.E., Kellog, T.D., Zinn, S.A., Govoni, K.E., Reed, S.A., 2018. Evaluation of the Nova Vet Meter for sheep-side monitoring of β-hydroxybutyric acid (BHBA) and description of ewe BHBA during late gestation in three flocks from the Northeastern U.S. Research in Veterinary Science 118, 491-497. https://doi.org/10.1016/j.rvsc.2018.05.002
  • Kabara, E., Sordillo, L.M., Holcombe, S., Contreras, G.A., 2014. Adiponectin links adipose tissue function and monocyte inflammatory responses during bovine metabolic stress. Comparative Immunology, Microbiology and Infectious Diseases 37, 49–58. https://doi.org/10.1016/j.cimid.2013.10.007
  • Karagiannis, I., Panousis, N., Kiossis, E., Tsakmakidis, I., Lafi, S., Arsenos, G., Boscos, C., Brozos, C., 2014. Associations of pre-lambing body condition score and serum -hydroxybutyric acid and non-esterified fatty acids concentrations with periparturient health of Chios dairy ewes. Small Ruminant Research 120(1), 164-173. https://doi.org/10.1016/j.smallrumres.2014.05.001.
  • Karapehlivan, M., Atakisi, E., Atakisi, O., Yucayurt, R., Pancarci, S.M., 2007. Blood biochemical parameters during the lactation and dry period in Tuj ewes. Small Ruminant Research 73, 267–271. https://doi.org/10.1016/j.smallrumres.2006.12.006
  • Kessler, E.C., Gross, J.J., Bruckmaier, R.M., Albrecht, C., 2014. Cholesterol metabolism, transport, and hepatic regulation in dairy cows during transition and early lactation. Journal of Dairy Science 97, 1–10. https://doi.org/10.3168/jds.2014-7926
  • Komatsu, T., Itoh, F., Sakumoto, R., Hodate, K., Obara, Y., Kushibiki, S., 2007. Changes in the gene expression of adiponectin and glucose transporter 12 (GLUT12) in lactating and non-lactating cows. Animal Science Journal 78, 98–102. https://doi.org/98-102 10.1111/j.1740-0929.2006. 00411.x
  • Kushibiki, S., 2011. Tumor necrosis factor-a-induced inflammatory responses in cattle. Animal Science Journal 82, 504–511. https://doi.org/10.1111/j.1740-0929.2011.00931.x
  • Küçükşen, D.U., 2017. Koyunlarda Doğum Sonrası Erken Laktasyon Döneminde Leptin ve Ghrelin Seviyelerin Değişimleri. . Atatürk Üniversitesi Veteriner Bilimleri Dergisi 12(3), 269-275. https://doi.org/10.17094/ataunivbd.299378
  • Laeger, T., Sauerwein, H., Tuchscherer, A., Bellmann, O., Metges, C.C., Kuhla, B., 2013. Concentrations of Hormones and Metabolites in Cerebrospinal Fluid and Plasma of Dairy Cows During the Periparturient Period. Journal of Dairy Science 96(5), 2883-93. https://doi.org/10.3168/jds.2012-5909
  • Lager, K., Jordan, E., 2012. The Metabolic Profile for the Modern Transition Dairy Cow. Mid-South Ruminant Nutrition Conference. Grapevine, Texas
  • Manat, T.D., Chaudhary, S.S., Singh, V.K., Patel, S.B., Puri, G. 2016. Hematobiochemical profile in Surti goats during post-partum period. Veterinary World 9, 19-24. https://doi.org/10.14202/vetworld.2016.19-24
  • Matarese, G., Moschos, S., Mantzoros, C.S., 2005. Leptin in Immunology. The Journal of Immunology 174 (6), 3137-3142. https://doi.org/10.4049/jimmunol.174.6.3137
  • Merhan, O., Özcan, A., 2010. Peripartum Dönemdeki Koyunlarda Seruloplazmin, Haptoglobin, Fibrinojen, Albümin ve Transferrin Düzeylerinin Araştırılması. Erciyes Üniversitesi Veteriner Fakültesi Dergisi 7(1), 13- 20.
  • Mohammadi, V., Anassori, E., Jafari, S., 2016. Measure of energy related biochemical metabolites changes during peri-partum period in Makouei breed sheep Veterinary Research Forum 7(1), 35 – 39.
  • Nazifi, S., Saeb, M., Ghavami, S.M., 2002. Serum lipid profile in Iranian fat-tailed sheep in late pregnancy, at parturition and during the post-parturition period. Journal of Research in Veterinary Medicine 49, 9-12. https://doi.org/10.1046/j.1439-0442.2002.00405.x
  • Nowroozi-Asl, A., Aarabi, N., Rowshan-Ghasrodashti, A., 2016. Ghrelin and its correlation with leptin, energy related metabolites and thyroidal hormones in dairy cows in transitional period. Polish Journal of Veterinary Sciences 19(1), 197–204. https://doi.org/10.1515/pjvs-2016-0024
  • Ohtani, Y., Takahashi, T., Sato, K., Ardiyanti, A., Song, SH, Sato, R., Onda, K., Wada, Y., Obara, Y., Suzuki, K., Hagino, A., Roh, S.G., Katoh, K., 2012. Changes in circulating adiponectin and metabolic hormone concentrations during periparturient and lactation periods in Holstein dairy cows. Animal Science Journal 83(12), 788-795. https://doi.org/10.1111/j.1740-0929.2012.01029.x
  • Peterson, A.B., Orth, M.W., Goff, J.P., Beede, D.K., 2005. Periparturient Responses of Multiparous Holstein Cows Fed Different Dietary Phosphorus Concentrations Prepartum. Journal of Dairy Science 88, 3582–3594. https://doi.org/10.3168/jds.S0022-0302(05)73043-5
  • Piccione, G., Caola, G., Giannetto, C., Grasso, F., Runzo, S.C., Zumbo, A., Pennisi, P., 2009. Selected biochemical serum parameters in ewes during pregnancy, post-parturition, lactation and dry period. Animal Science Papers and Reports 27(4), 321-330.
  • Piccione, G., Messina, V., Schembari, A., Casella, S., Giannetto, C., Alberghina, C., 2011. Pattern of serum protein fractions in dairy cows during different stages of gestation and lactation. Journal of Dairy Research 78 (4), 421-425. https://doi.org/10.1017/S0022029911000562
  • Popovic, V., 2006. Ghrelin. Current Opinion in Endocrinology 13, 70–75. https://doi.org/10.1097/01.med.0000200527.16276.e6
  • Proloa, P., Wonga, M., Licinioa, J., 1998. Leptin. The International Journal of Biochemistry & Cell Biology 30(12), 1285-1290. https://doi.org/10.1016/S1357-2725(98)00094-6
  • Rasmussen, A.N., Nielsen, M.O., Tauson, A.H., Blache, D., 2004. Leptin and lactogenesis in the periparturient dairy goat. Journal of Animal and Feed Sciences 13, 555−558. https://doi.org/10.22358/jafs/74034/2004
  • Rukkwamsuk, T., Wensing, T., Geelen, M.J.H., 1998. Effect of Overfeeding During the Dry Period on Regulation of Adipose Tissue Metabolism in Dairy Cows During the Periparturient Period. Journal of Dairy Science 81, 2904–2911. https://doi.org/10.3168/jds.S0022-0302(98)75851-5
  • Sadjadian, R., Seifi, H.A., Mohri, M., Naserian, A.A., Farzaneh, N., 2013. Variations of energy biochemical metabolites in periparturient dairy Saanen goats. Comparative Clinical Pathology 22, 449–456. https://doi.org/ 10.1007/s00580-012-1431-8
  • Schlegel, G., Ringseis, R., Keller, J., Schwarz, FJ., Eder, K., 2012. Changes in the expression of hepatic genes involved in cholesterol homeostasis in dairy cows in the transition period and at different stages of lactation. Journal of Dairy Science 95, 3826–3836. https://doi.org/10.3168/jds.2011-5221
  • Seifi, H.A., Dooz, M.G., Mohri, M., Naghadeh, B.D., Farzaneh, N., 2007. Variations of energy-related biochemical metabolites during transition period in dairy cows. Comparative Clinical Pathology 16, 253–258. https://doi.org/10.1007/s00580-007-0682-2
  • Sepúlveda-Varas, P., Huzzey, J.M., Weary, D.M., Keyserlingk, M.A.G., 2012. Behaviour, illness and management during the periparturient period in dairy cows. Animal Production Science 53(9), 988-999. https://doi.org/10.1071/AN12286
  • Sethi, J.K., Hotamisligil, G.S., 1999. The role of TNF alpha in adipocyte metabolism. Cell & Developmental Biology 10, 19-29. https://doi.org/10.1006/scdb.1998.0273
  • Sevinç, M., Başoğlu, A., Birdane, F., Gökçen, M., 1999. Sütçü Sığırlarda Kuru Dönem Doğum ve Doğum Sonrası Metabolik Profildeki Değişiklikler. Turkish Journal of Veterinary & Animal Sciences 3, 475-478.
  • Soares, G.S.L., Souto, R.J.T., Cajueiro, J.F.P., Afonso, J.A.B., Rego, R.O., Macêdo, A.T.M., Soares, P.C., Mendonça, C.L., 2018. Adaptive changes in blood biochemical profile of dairy goats during the period of transition. Revue de Medecine Veterinaire 169, 65-75.
  • Stojević, Z., Piršljin, J., Milinković-Tur, S., Zdelar-Tuk, M., Ljubić, B.B., 2005. Activities of AST, ALT and GGT in clinically healthy dairy cows during lactation and in the dry period. Veterinarski Arhiv., 75 (1), 67-73.
  • Temizel, E.M., Cihan, H., Levent, P., Sarıl, A., Özarda, Y., Yılmaz, Z., 2018. Comparison of pre- and postpartum serum leptin, ghrelin, and lipid levels in sheep. Turkish Journal of Veterinary & Animal Sciences 42, 177-183. https://doi.org/10.3906/vet-1705-87
  • Tharwat, M., Ali, A., Al-Sobayil, F., 2015. Hematological and biochemical profiles in goats during the transition period. Comparative Clinical Pathology 24, 1–7. https://doi.org/ 10.1007/s00580-013-1842-1
  • Trevisi, E., Amadori, M., Cogrossi, S., Razzuoli, E., Bertoni, G., 2012. Metabolic stress and inflammatory response in high-yielding, periparturient dairy cows. Res. Vet. Sci., 93, 695–704. https://doi.org/10.1016/j.rvsc.2011.11.008
  • Tunç, A.C., Birdane, F.M., Uyarlar, C., Yipel, F.A., Gültepe, E.E., Başer, D.F., Acar, A., 2017. Geçiş Dönemindeki Süt İneklerinde Damar İçi Novacoc® Uygulamasının Metabolik Profil Üzerine Etkileri. Kocatepe Veterinary Journal 10(4), 278-286. https://doi.org/10.5578/kvj.61911.
  • Turk, R., Podpecan, O., Mrkun, J., Kosec, M., Flegar-Mestric, Z., Perkov, S., Starice, J., Robic, M., Belic, M., Zrimsek, P., 2013. Lipid mobilisation and oxidative stress as metabolic adaptation processes in dairy heifers during transition period. Animal Reproduction Science 141, 109– 115. https://doi.org/10.1016/j.anireprosci.2013.07.014
  • Uyanık, F., Güvenç, K., Gültekin, M., Gürbulak, K., 2009. Koyunlarda Gebeliğin Değişik Dönemlerinde Leptin ve Progesteron Düzeyleri. Erciyes Üniversitesi Veteriner Fakültesi Dergisi 6(1), 31-36.
  • Vandehaar, M.J., Yousif, G., Sharma, B.K., Herdt, T.H., Emery, R.S., Allen, M.S., Liesman, J.S., 1999. Effect of Energy and Protein Density of Prepartum Diets on Fat and Protein Metabolism of Dairy Cattle in the Periparturient Period. Journal of Dairy Science 82, 1282–1295. https://doi.org/10.3168/jds.S0022-0302(99)75351-8
  • Vargová, M., Kováč, G., 2016. Periparturient Period in Terms of Body Condition Score and Selected Parameters of Hormonal Profiles. Folia Veterinaria., 60(1), 63-69. https://doi.org/ 10.1515/FV-2016-0010
  • Vostry, L., Milerski, M., Schmidova, J., Vostra-Vydrova, H., 2018. Genetic diversity and effect of inbreeding on litter size of the Romanov sheep. Small Ruminant Research 168, 25-31. https://doi.org/10.1016/j.smallrumres.2018.09.004
  • Yehia, S.G., Salem, N.Y., 2015. Assessment of Some Biochemical Parameters in Dairy Cows during Transition Period. International Journal of Veterinary Science 4(4), 227-230.
There are 65 citations in total.

Details

Primary Language English
Subjects Veterinary Sciences (Other)
Journal Section Research Article
Authors

Özlem Bicici 0000-0001-9210-4744

Mehmet Çağrı Karakurum 0000-0002-0767-883X

Project Number 0566-DR-19
Publication Date May 2, 2024
Submission Date April 3, 2024
Acceptance Date May 2, 2024
Published in Issue Year 2024 Volume: 12 Issue: 1

Cite

APA Bicici, Ö., & Karakurum, M. Ç. (2024). Investigation of Adiponectin, Leptin and Ghrelin Levels and Evaluation of Metabolic Profiles in the Periparturient Period in Romanov Sheep. Mehmet Akif Ersoy University Journal of Health Sciences Institute, 12(1), 26-39. https://doi.org/10.24998/maeusabed.1464209
AMA Bicici Ö, Karakurum MÇ. Investigation of Adiponectin, Leptin and Ghrelin Levels and Evaluation of Metabolic Profiles in the Periparturient Period in Romanov Sheep. Mehmet Akif Ersoy University Journal of Health Sciences Institute. May 2024;12(1):26-39. doi:10.24998/maeusabed.1464209
Chicago Bicici, Özlem, and Mehmet Çağrı Karakurum. “Investigation of Adiponectin, Leptin and Ghrelin Levels and Evaluation of Metabolic Profiles in the Periparturient Period in Romanov Sheep”. Mehmet Akif Ersoy University Journal of Health Sciences Institute 12, no. 1 (May 2024): 26-39. https://doi.org/10.24998/maeusabed.1464209.
EndNote Bicici Ö, Karakurum MÇ (May 1, 2024) Investigation of Adiponectin, Leptin and Ghrelin Levels and Evaluation of Metabolic Profiles in the Periparturient Period in Romanov Sheep. Mehmet Akif Ersoy University Journal of Health Sciences Institute 12 1 26–39.
IEEE Ö. Bicici and M. Ç. Karakurum, “Investigation of Adiponectin, Leptin and Ghrelin Levels and Evaluation of Metabolic Profiles in the Periparturient Period in Romanov Sheep”, Mehmet Akif Ersoy University Journal of Health Sciences Institute, vol. 12, no. 1, pp. 26–39, 2024, doi: 10.24998/maeusabed.1464209.
ISNAD Bicici, Özlem - Karakurum, Mehmet Çağrı. “Investigation of Adiponectin, Leptin and Ghrelin Levels and Evaluation of Metabolic Profiles in the Periparturient Period in Romanov Sheep”. Mehmet Akif Ersoy University Journal of Health Sciences Institute 12/1 (May 2024), 26-39. https://doi.org/10.24998/maeusabed.1464209.
JAMA Bicici Ö, Karakurum MÇ. Investigation of Adiponectin, Leptin and Ghrelin Levels and Evaluation of Metabolic Profiles in the Periparturient Period in Romanov Sheep. Mehmet Akif Ersoy University Journal of Health Sciences Institute. 2024;12:26–39.
MLA Bicici, Özlem and Mehmet Çağrı Karakurum. “Investigation of Adiponectin, Leptin and Ghrelin Levels and Evaluation of Metabolic Profiles in the Periparturient Period in Romanov Sheep”. Mehmet Akif Ersoy University Journal of Health Sciences Institute, vol. 12, no. 1, 2024, pp. 26-39, doi:10.24998/maeusabed.1464209.
Vancouver Bicici Ö, Karakurum MÇ. Investigation of Adiponectin, Leptin and Ghrelin Levels and Evaluation of Metabolic Profiles in the Periparturient Period in Romanov Sheep. Mehmet Akif Ersoy University Journal of Health Sciences Institute. 2024;12(1):26-39.