The effective control method for disturbance rejection is presented in this paper. The new control method is derived by combining the internal model control (I.M.C) with an approximate inverse system and optimal control. The disturbance rejection property of the limiting form was discussed, which was derived by letting the weighting matrix with the state vector tend to infinity in a standard linear quadratic problem. Experimental results reveal that the proposed method leads to multiple effect for the above control methods. Further, the proposed control method is applicable to multivariable systems.