A rare case of adenosquamous carcinoma of the larynx was reported. The patient was a 79-year-old female who visited our clinic with complaints of dyspnea and hoarseness which had lasted for about four months. A large tumor extending into the supraglottic region was found. The histological diagnosis of a biopsied specimen was squamous cell carcinoma. Total laryngectomy and radical neck dissection on the right side were performed. The ultimate diagnosis of the removed tumor was adenosquamous carcinoma. There was a lymph node metastasis which consisted of squamous cell carcinoma only in the right mid-internal jugular nodes. The patient was free from recurrence for nine months, but died as a result of a hemorrhage in her digestive tract and pneumonia.