L-carnosine (βalanyl 1-histidine), used in the form of a dental cone in the amount of 5mg per root, proved successful in relieving pains associated with dental extraction, as endorsed by the inhibition of edemata and postoperative pain complaints.
This antiinflammatory effect of 1-carnosine is believed to be found in the promotion of defense mechanism inherent in the vital tissues. The effective dosage of the present clinical study corresponds to 1/35 of what is usually contained in the vital tissue.