PTMVision: An Interactive Visualization Platform for Post-Translational Modifications of Proteins
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Date
2023
Journal Title
Journal ISSN
Volume Title
Publisher
The Eurographics Association
Abstract
In recent years, proteins have been shown to carry many more post-translational modifications (PTMs) than originally thought. The visualization of proteins along with their PTMs facilitates exploration and understanding of the effects of these PTMs on the protein structure, function, and interactions with other proteins. Therefore, we developed PTMVision, an interactive webbased visualization. We combine information about PTMs in the primary sequence with a two-dimensional representation of the protein's tertiary structure using a presence-absence map and a modified contact map that relates PTMs with the spatial arrangement of proteins without the need of a 3D structure. The prototype of PTMVision is part of the TueVis Visualization Server and is available at https://ptmvision-tuevis.cs.uni-tuebingen.de/.
Description
@inproceedings{10.2312:evp.20231067,
booktitle = {EuroVis 2023 - Posters},
editor = {Gillmann, Christina and Krone, Michael and Lenti, Simone},
title = {{PTMVision: An Interactive Visualization Platform for Post-Translational Modifications of Proteins}},
author = {Hackl, Simon and Jachmann, Caroline and Harbig, Theresa and Witte Paz, Mathias and Nieselt, Kay},
year = {2023},
publisher = {The Eurographics Association},
ISBN = {978-3-03868-220-2},
DOI = {10.2312/evp.20231067}
}