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Impact of Patient Personality on Adherence to Oral Anti-Cancer Medications: An Opportunity?
ABSTRACT
Adherence to prescribed oral anticancer therapy is an important determinant of patient outcomes, including progression-free and overall survival. While many factors (e.g., medication side effects and out-of-pocket costs, problems with insurance authorization and timely medication refills) can affect adherence, one that is relatively unexplored is the impact of a patient’s attitude and personality. Patient personality influences medication adherence and persistence in non-malignant chronic conditions such as cardiovascular disease and diabetes. In breast cancer and chronic myeloid leukemia, studies suggest that personality also affects adherence to oral chemotherapy which can be targeted to improve adherence. Here, we highlight the opportunity of incorporating patient personality as interventions to oral cancer therapy adherence, and discuss current barriers to implementation.
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Copyright
© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.