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Currently submitted to: Interactive Journal of Medical Research

Date Submitted: Dec 1, 2023

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Screening for Depression Using Natural Language Processing (NLP): A Literature Review

  • Bazen Gashaw Teferra; 
  • Alice Rueda; 
  • Hilary Pang; 
  • Rick Valenzano; 
  • Reza Samavi; 
  • Sridhar Krishnan; 
  • Venkat Bhat

ABSTRACT

Background:

Depression is a prevalent global mental health disorder with substantial individual and societal impacts. Natural Language Processing (NLP), a branch of artificial intelligence, offers the potential for improving depression screening by extracting meaningful information from textual data, but challenges and ethical considerations exist.

Objective:

This literature review aims to explore existing NLP methods for detecting depression, discuss successes and limitations, address ethical concerns, and highlight potential biases.

Methods:

The review synthesizes research on NLP techniques, historical NLP development, depression detection methods, classification models, datasets, and ethical considerations. Cross-cultural and multilingual perspectives are discussed, along with the integration of depression screening in the RDoC framework. The review also examines validation and evaluation metrics, ethical challenges, and future directions.

Results:

NLP techniques, including sentiment analysis, linguistic markers, and deep learning models, offer practical tools for depression screening. Supervised and unsupervised machine learning models and large language models like Transformers have demonstrated high accuracy in a variety of application domains. However, ethical concerns related to privacy, bias, interpretability, and lack of regulations to protect individuals arise. Furthermore, cultural and multilingual perspectives highlight the need for culturally sensitive models.

Conclusions:

NLP presents opportunities to revolutionize depression detection, but significant challenges persist. Ethical concerns must be addressed, governance guidance is needed to mitigate risks, and cross-cultural perspectives must be integrated. Future directions include improving interpretability, personalization, and increased collaboration with domain experts such as data scientists, ML engineers, etc. NLP's potential to enhance mental health care remains promising, depending on overcoming obstacles and continuing innovation.


 Citation

Please cite as:

Teferra BG, Rueda A, Pang H, Valenzano R, Samavi R, Krishnan S, Bhat V

Screening for Depression Using Natural Language Processing (NLP): A Literature Review

JMIR Preprints. 01/12/2023:55067

DOI: 10.2196/preprints.55067

URL: https://preprints.jmir.org/preprint/55067

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