Epidemiology and Control of Infectious Diseases of Salmonids in the Columbia River Basin, 1987 Annual Report.
The Department of Microbiology at Oregon State University with funding from the Bonneville Power Administration has been conducting a study concerning the epidemiology and control of three fish pathogens which cause major disease problems in salmonids of the Columbia River basin. The pathogens studied include Cera to myxa Shasta, the myxosporean parasite which causes ceratomyxosis; Renibacterium salmoninarum, the bacterium which is the etiological agent of bacterial kidney disease; and the rhabdovirus which causes infectious hematopoietic necrosis (IHN). During this project, the host and geographic range of C. Shasta have been more precisely determined and the known geographic range has been significantly expanded. The effects of the parasite on fish migrating through the Columbia River and on their introduction into salt water have been examined. Similar studies have been conducted with R. salmoninarum and it has been shown that bacterial kidney disease occurs at all life stages of salmonids and is responsible for mortality in both fresh and salt water. It has also been demonstrated that different isolates of R. salmoninarum have different antigenic composition. Results of demonstration projects designed to control IHN by using UV treated water for early rearing of salmonid fry were equivocal. The scope of the project was considerably narrowed and focused during the past two years The project has concentrated on a study concerning the biology of C. Shasta and the identification of potential chemotherapeutants for control of bacterial kidney disease. The emphasis of work on C. Shasta has been its pathogenesis. This aspect of the parasite has been investigated using histopathologic and immunologic methodology. Mode of transmission, the nature of the infectious stage, and potential intermediate hosts of the parasite have also been areas of active research. Classes of chemotherapeutants with the highest potential for efficacy against R. salmoninarum have been identified through literature searches and consultation with pharmacologists. Experimental drugs have been requested and received from several pharmaceutical manufacturers. The in vitro sensitivity of R. salmoninarum and other selected fish pathogens to more than 100 antimicrobial compounds has been tested. The project is related to measure 704(h)(2)(d) of the Columbia River Basin Fish and Wildlife Program. The results will contribute to fish health which will directly contribute to the protection of fish.
- Research Organization:
- Oregon State Univ., Corvallis, OR (United States)
- Sponsoring Organization:
- United States. Bonneville Power Administration.
- DOE Contract Number:
- 1983BP11987
- OSTI ID:
- 758251
- Report Number(s):
- DOE/BP-11987-3; R&D Project: 1983-312-00; TRN: AH200022%%97
- Resource Relation:
- Other Information: PBD: 1 Jan 1989
- Country of Publication:
- United States
- Language:
- English
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Epidemiology and Control of Infectious Diseases of Salmonids in the Columbia River Basin, 1986 Annual Report.
Epidemiology and Control of Infectious Diseases of Salmonids in the Columbia River Basin, 1983 Annual Report.