IgD Multiple Myeloma with Renal Involvement: Case Report

Hirofumi HOMAN; Yoshinobu OHTUBO; Hirohide ITO; Kazuhiro AZUMA; Yuichiro YASUMOTO; Hideyuki OHTUKA; Kenji UOMIZU; Wataru YAMASHITA; Shinichiro UEMURA; Kazuya OHSAKI; Akira NAKAJIMA; Ryuji HARADA; Terukatu ARIMA

doi:10.2169/internalmedicine1962.29.212

Hirofumi HOMAN, Yoshinobu OHTUBO, Hirohide ITO, Kazuhiro AZUMA, Yuichiro YASUMOTO, Hideyuki OHTUKA, Kenji UOMIZU, Wataru YAMASHITA, Shinichiro UEMURA, Kazuya OHSAKI, Akira NAKAJIMA, Ryuji HARADA, Terukatu ARIMA

Author information

Hirofumi HOMAN
The Second Department of Internal Medicine, Faculty of Medicine, Kagoshima University
Yoshinobu OHTUBO
The Second Department of Internal Medicine, Faculty of Medicine, Kagoshima University
Hirohide ITO
The Second Department of Internal Medicine, Faculty of Medicine, Kagoshima University
Kazuhiro AZUMA
The Second Department of Internal Medicine, Faculty of Medicine, Kagoshima University
Yuichiro YASUMOTO
The Second Department of Internal Medicine, Faculty of Medicine, Kagoshima University
Hideyuki OHTUKA
The Second Department of Internal Medicine, Faculty of Medicine, Kagoshima University
Kenji UOMIZU
The Second Department of Internal Medicine, Faculty of Medicine, Kagoshima University
Wataru YAMASHITA
The Second Department of Internal Medicine, Faculty of Medicine, Kagoshima University
Shinichiro UEMURA
The Nanpu Hospital
Kazuya OHSAKI
Imamura Hospital
Akira NAKAJIMA
Imamura Hospital
Ryuji HARADA
The Second Department of Internal Medicine, Faculty of Medicine, Kagoshima University
Terukatu ARIMA
The Second Department of Internal Medicine, Faculty of Medicine, Kagoshima University

Keywords: IgD, Multiple myeloma, Renal failure

JOURNAL FREE ACCESS

1990 Volume 29 Issue 2 Pages 212-215

DOI https://doi.org/10.2169/internalmedicine1962.29.212

Details

Abstract

IgD multiple myeloma is a unique type of multiple myeloma which is characterized by increased serum IgD and IgD type M-component in immunoelectrophoresis. It frequently shows renal involvement but it is a rare form of myeloma. The distinctive features of IgD myeloma are the dominance in males, high frequency in younger persons, and the uncertain appearance of M-componentin serum electrophoresis. We experienced 3 cases of IgD multiple myeloma with renal failure which required hemodialysis before IgD myeloma was diagnosed. It is important to consider IgD myeloma when treating the patients with renal involvement of unknown origin.

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