The pyridoxylidene-taurineatocopper(II) complex [Cu(C₁₀H₁₃N₂O₅S)₂·H₂O] was synthesized by the reaction of the taurine pyridoxal Schiff base and copper acetate in a water-ethanol solution, and determined by an X-ray diffraction method. The complex crystallized in a monoclinic system with space group C2/c, and a = 23.908(5)Å, b = 7.7562(16)Å, c = 17.266(4)Å, β = 130.45(3)°. V = 2436.3(9)ų, Z = 4, D_x = 1.712 Mg/m³. The neighboring molecules in the complex are connected by three types of hydrogen bonds, obtaining a three-dimensional network supramolecular architecture.