ESTABLISHMENT OF LYMPHOBLASTOID CELL LINES FROM PERIPHERAL BLOOD AND LYMPH NODE OF JAPANESE PATIENTS WITH VARIOUS DISEASES
1971 Volume 62 Issue 5 Pages 413-417_2
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1971 Volume 62 Issue 5 Pages 413-417_2
Twelve lymphoblastoid cell lines have been established from peripheral blood and lymph node of patients with malignant and benign diseases. The sequential morphological changes of peripheral leucocyte cultures are, first, the emergence of macrophages, then intimate interactions between the macrophages and surviving lymphocytes, and eventual blastogenic transformation of the lymphocytes.
