Penile agenesis (afallia) in pueros


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Abstract

Introduction. Penile agenesis (aphallia) is an extremely rare congenital defect characterized by the complete absence of the penis in a child with a male karyotype 46XY.

Material. The analysis of the literature on keywords in the Pubmed and Medline databases was carried out.

Results. The incidence of aphallia is estimated 1 out of 10-40 million newborn boys. Aphallia, in spite of its rarity, is a congenital defect which is thoroughly described in the medical literature. The combination of agenesis of the penis with other congenital anomalies often leads to death in such children. Currently, it is believed that these patients should be left with their genetic male sex, therefore, there is a difficult dilemma of choosing the optimal method and age for creating the neophallus and neourethra.

Conclusions. The rarity of the aphallia determines the lack of publications covering the long-term results of phalloplasty in both children and adults.

About the authors

I. M. Kagantsov

Institute of Perinatology and Pediatrics, Almazov National Medical Research Centre;
Pitirim Sorokin Syktyvkar State University

Author for correspondence.
Email: ilkagan@rambler.ru
ORCID iD: 0000-0002-3957-1615

Ilya M. Kagantsov, MD, Dr.Sc. (med), associate professor, chief researcher at the laboratory for surgical correction of congenital and hereditary pathologies at the Institute of Perinatology and Pediatrics in the Almazov National Medical Research Center; professor at department of surgery in the Pitirim Sorokin State University

197341, St. Petersburg,

Syktyvkar, 167001

Russian Federation

V. I. Dubrov

2nd City Children’s Clinical Hospital

Email: fake@neicon.ru
ORCID iD: 0000-0002-3705-1288

Minsk, 167000

Belarus

V. V. Sizonov

Rostov-on-Don Regional Children’s Clinical Hospital;
Rostov State Medical University

Email: fake@neicon.ru
ORCID iD: 0000-0001-9145-8671

344015, Rostov-on-Don,

344022, Rostov-on-Don

Russian Federation

V. G. Bairov

Institute of Perinatology and Pediatrics, Almazov National Medical Research Centre

Email: fake@neicon.ru
ORCID iD: 0000-0002-8446-830X

St-Petersburg, 197349

Russian Federation

A. A. Sukhotskaya

Institute of Perinatology and Pediatrics, Almazov National Medical Research Centre

Email: fake@neicon.ru

St-Petersburg, 197349

Russian Federation

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